Microbiology and Immunology

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2025

Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W et al.. 2025. AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.. Sci Adv. 11(34):eadv6937.

Du Y, Faz-Lopez B, Kioon MDominique, Cenac C, Pierides M, Lakin KS, Spiera RF, Chaumeil J, Truchetet M-E, Gordon JK et al.. 2025. Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis.. J Exp Med. 222(3)

Smith AA, Su H, Wallach J, Liu Y, Maiello P, H Borish J, Winchell C, Simonson AW, Lin PLing, Rodgers M et al.. 2025. A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.. Nat Microbiol. 10(2):468-481.

Smith AA, Su H, Wallach J, Liu Y, Maiello P, H Borish J, Winchell C, Simonson AW, Lin PLing, Rodgers M et al.. 2025. A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.. Nat Microbiol. 10(2):468-481.

Smith AA, Su H, Wallach J, Liu Y, Maiello P, H Borish J, Winchell C, Simonson AW, Lin PLing, Rodgers M et al.. 2025. A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.. Nat Microbiol. 10(2):468-481.

Mishra S, Singh PRanjan, Hu X, Lopez-Quezada L, Jinich A, Jahn R, Geurts L, Shen N, DeJesus MA, Hartman T et al.. 2025. Candidate transmission survival genome of Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 122(10):e2425981122.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al.. 2025. Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.

Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al.. 2025. Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.

Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al.. 2025. Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.

Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al.. 2025. Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.

Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al.. 2025. Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.

Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al.. 2025. Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al.. 2025. A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al.. 2025. A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al.. 2025. A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.

Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al.. 2025. Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.