Microbiology and Immunology

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2016
Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan C.  2016.  Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.. Proc Natl Acad Sci U S A. 113(49):E7947-E7956.
2015
Mackley EC, Houston S, Marriott CL, Halford EE, Lucas B, Cerovic V, Filbey KJ, Maizels RM, Hepworth MR, Sonnenberg GF et al..  2015.  CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.. Nat Commun. 6:5862.
Frykman PK, Nordenskjöld A, Kawaguchi A, Hui TT, Granström AL, Cheng Z, Tang J, Underhill DM, Iliev ID, Funari VA et al..  2015.  Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study.. PLoS One. 10(4):e0124172.
Frykman PK, Nordenskjöld A, Kawaguchi A, Hui TT, Granström AL, Cheng Z, Tang J, Underhill DM, Iliev ID, Funari VA et al..  2015.  Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study.. PLoS One. 10(4):e0124172.
Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA, Kaye J.  2015.  The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. Nat Immunol. 16(6):599-608.
Dai R, Geders TW, Liu F, Park SWoong, Schnappinger D, Aldrich CC, Finzel BC.  2015.  Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.. J Med Chem. 58(13):5208-17.
Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al..  2015.  Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.
Tang J, Iliev ID, Brown J, Underhill DM, Funari VA.  2015.  Mycobiome: Approaches to analysis of intestinal fungi.. J Immunol Methods. 421:112-21.
Park SWoong, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC et al..  2015.  Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.. Chem Biol. 22(1):76-86.
Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED et al..  2015.  Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.. ACS Chem Biol. 10(2):364-71.
Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al..  2015.  Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.
2014
Janovitz T, Sadelain M, Falck-Pedersen E.  2014.  Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints.. Virol J. 11:15.
Lam E, Stein S, Falck-Pedersen E.  2014.  Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade.. J Virol. 88(2):974-81.
Fung TC, Artis D, Sonnenberg GF.  2014.  Anatomical localization of commensal bacteria in immune cell homeostasis and disease.. Immunol Rev. 260(1):35-49.
Sander AF, Lavstsen T, Rask TS, Lisby M, Salanti A, Fordyce SL, Jespersen JS, Carter R, Deitsch K, Theander TG et al..  2014.  DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.. Nucleic Acids Res. 42(4):2270-81.
Janovitz T, Oliveira T, Sadelain M, Falck-Pedersen E.  2014.  Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing.. J Virol. 88(5):2481-8.
Lam E, Falck-Pedersen E.  2014.  Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells.. J Virol. 88(24):14426-39.
2013
Heinberg A, Siu E, Stern C, Lawrence EA, Ferdig MT, Deitsch K, Kirkman L.  2013.  Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.. Mol Microbiol. 88(4):702-12.
Qiu J, Guo X, Chen Z-ME, He L, Sonnenberg GF, Artis D, Fu Y-X, Zhou L.  2013.  Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora.. Immunity. 39(2):386-99.
Janovitz T, Klein IA, Oliveira T, Mukherjee P, Nussenzweig MC, Sadelain M, Falck-Pedersen E.  2013.  High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration.. J Virol. 87(15):8559-68.
Hepworth MR, Monticelli LA, Fung TC, Ziegler CGK, Grunberg S, Sinha R, Mantegazza AR, Ma H-L, Crawford A, Angelosanto JM et al..  2013.  Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.. Nature. 498(7452):113-7.
Zhong S, Fei Z, Chen Y-R, Zheng Y, Huang M, Vrebalov J, McQuinn R, Gapper N, Liu B, Xiang JZ et al..  2013.  Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening.. Nat Biotechnol. 31(2):154-9.
Noti M, Wojno EDTait, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA et al..  2013.  Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.. Nat Med. 19(8):1005-13.
Siracusa MC, Saenz SA, Wojno EDTait, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM et al..  2013.  Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.. Immunity. 39(6):1158-70.
2012
Stein SC, Lam E, Falck-Pedersen E.  2012.  Cell-specific regulation of nucleic acid sensor cascades: a controlling interest in the antiviral response.. J Virol. 86(24):13303-12.