Microbiology and Immunology

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Found 284 results

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2020

Siao MC, Borner J, Perkins SL, Deitsch KW, Kirkman LA. 2020. Evolution of Host Specificity by Malaria Parasites through Altered Mechanisms Controlling Genome Maintenance.. mBio. 11(2)

Gengenbacher M, Zimmerman MD, Sarathy JP, Kaya F, Wang H, Mina M, Carter C, Hossen MAmir, Su H, Trujillo C et al.. 2020. Tissue Distribution of Doxycycline in Animal Models of Tuberculosis.. Antimicrob Agents Chemother. 64(5)

Kirkman LA, Deitsch KW. 2020. Vive la Différence: Exploiting the Differences between Rodent and Human Malarias.. Trends Parasitol. 36(6):504-511.

2019

Ban Y, Dong W, Zhang L, Zhou T, Altiti AS, Ali K, Mootoo DR, Blaho VA, Hla T, Ren Y et al.. 2019. Abrogation of Endogenous Glycolipid Antigen Presentation on Myelin-Laden Macrophages by D-Sphingosine Ameliorates the Pathogenesis of Experimental Autoimmune Encephalomyelitis.. Front Immunol. 10:404.

Quezada LLopez, Silve S, Kelinske M, Liba A, Gonzalez CDiaz, Kotev M, Goullieux L, Sans S, Roubert C, Lagrange S et al.. 2019. Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.. mBio. 10(4)

Wu J, Mu R, Sun M, Zhao N, Pan M, Li H, Dong Y, Sun Z, Bai J, Hu M et al.. 2019. Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .. ACS Infect Dis. 5(7):1087-1104.

Quezada LLopez, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K et al.. 2019. Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .. ACS Infect Dis. 5(8):1433-1445.

Quezada LLopez, Li K, McDonald SL, Nguyen Q, Perkowski AJ, Pharr CW, Gold B, Roberts J, McAulay K, Saito K et al.. 2019. Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .. ACS Infect Dis. 5(8):1433-1445.

Zimmerman M, McDonald SL, Ho-Liang H-P, Porubsky P, Nguyen Q, Pharr CW, Perkowski AJ, Smith R, Schoenen FJ, Gold BS et al.. 2019. Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.. J Antibiot (Tokyo). 72(6):469-475.

McLean KJarrod, Straimer J, Hopp CS, Vega-Rodriguez J, Small-Saunders JL, Kanatani S, Tripathi A, Mlambo G, Dumoulin PC, Harris CT et al.. 2019. Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.. Sci Rep. 9(1):13131.

Early J, Ollinger J, Darby C, Alling T, Mullen S, Casey A, Gold B, Ochoada J, Wiernicki T, Masquelin T et al.. 2019. Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.. ACS Infect Dis. 5(2):272-280.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al.. 2019. Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.

Freire DMendes, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V et al.. 2019. An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.. Mol Cell. 73(6):1282-1291.e8.

Beites T, O'Brien K, Tiwari D, Engelhart CA, Walters S, Andrews J, Yang H-J, Sutphen ML, Weiner DM, Dayao EK et al.. 2019. Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.. Nat Commun. 10(1):4970.

Beites T, O'Brien K, Tiwari D, Engelhart CA, Walters S, Andrews J, Yang H-J, Sutphen ML, Weiner DM, Dayao EK et al.. 2019. Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.. Nat Commun. 10(1):4970.

Beites T, O'Brien K, Tiwari D, Engelhart CA, Walters S, Andrews J, Yang H-J, Sutphen ML, Weiner DM, Dayao EK et al.. 2019. Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.. Nat Commun. 10(1):4970.

Zhang X, Alexander N, Leonardi I, Mason C, Kirkman LA, Deitsch KW. 2019. Rapid antigen diversification through mitotic recombination in the human malaria parasite Plasmodium falciparum.. PLoS Biol. 17(5):e3000271.

Subramaniyam S, DeJesus MA, Zaveri A, Smith CM, Baker RE, Ehrt S, Schnappinger D, Sassetti CM, Ioerger TR. 2019. Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression.. BMC Bioinformatics. 20(1):603.

Wang K-J, Wang C, Dai L-H, Yang J, Huang H, Ma X-J, Zhou Z, Yang Z-Y, Xu W-D, Hua M-M et al.. 2019. Targeting an Autocrine Regulatory Loop in Cancer Stem-like Cells Impairs the Progression and Chemotherapy Resistance of Bladder Cancer.. Clin Cancer Res. 25(3):1070-1086.

2018

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M et al.. 2018. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.. Proc Natl Acad Sci U S A. 115(29):E6863-E6870.

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M et al.. 2018. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.. Proc Natl Acad Sci U S A. 115(29):E6863-E6870.

Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens A-J, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E et al.. 2018. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.. Biotechnol Bioeng. 115(4):885-899.

Dey AK, Cupo A, Ozorowski G, Sharma VK, Behrens A-J, Go EP, Ketas TJ, Yasmeen A, Klasse PJ, Sayeed E et al.. 2018. cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.. Biotechnol Bioeng. 115(4):885-899.