Microbiology and Immunology

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Found 251 results

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2016

Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan C. 2016. Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.. Proc Natl Acad Sci U S A. 113(49):E7947-E7956.

Korte J, Alber M, Trujillo CM, Syson K, Koliwer-Brandl H, Deenen R, Köhrer K, DeJesus MA, Hartman T, Jacobs WR et al.. 2016. Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.. PLoS Pathog. 12(12):e1006043.

2015

Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA, Kaye J. 2015. The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. Nat Immunol. 16(6):599-608.

Dai R, Geders TW, Liu F, Park SWoong, Schnappinger D, Aldrich CC, Finzel BC. 2015. Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.. J Med Chem. 58(13):5208-17.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al.. 2015. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.

Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L et al.. 2015. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.. Science. 349(6244):aac4223.

Park SWoong, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC et al.. 2015. Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.. Chem Biol. 22(1):76-86.

Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED et al.. 2015. Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.. ACS Chem Biol. 10(2):364-71.

Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al.. 2015. Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.

Garg A, Wesolowski D, Alonso D, Deitsch KW, Ben Mamoun C, Altman S. 2015. Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.. Proc Natl Acad Sci U S A. 112(38):11935-40.

Garg A, Wesolowski D, Alonso D, Deitsch KW, Ben Mamoun C, Altman S. 2015. Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.. Proc Natl Acad Sci U S A. 112(38):11935-40.

2014

Fung TC, Artis D, Sonnenberg GF. 2014. Anatomical localization of commensal bacteria in immune cell homeostasis and disease.. Immunol Rev. 260(1):35-49.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al.. 2014. Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al.. 2014. Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Sander AF, Lavstsen T, Rask TS, Lisby M, Salanti A, Fordyce SL, Jespersen JS, Carter R, Deitsch K, Theander TG et al.. 2014. DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.. Nucleic Acids Res. 42(4):2270-81.

Torgbor C, Awuah P, Deitsch K, Kalantari P, Duca KA, Thorley-Lawson DA. 2014. A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.. PLoS Pathog. 10(5):e1004170.

Coleman BI, Skillman KM, H Y Jiang R, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M et al.. 2014. A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.. Cell Host Microbe. 16(2):177-186.

2013

Shi C, Tiwari D, Wilson DJ, Seiler CL, Schnappinger D, Aldrich CC. 2013. Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation.. ACS Med Chem Lett. 4(12)

Kim J-H, O'Brien KM, Sharma R, Boshoff HIM, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC et al.. 2013. A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.. Proc Natl Acad Sci U S A. 110(47):19095-100.

Qiu J, Guo X, Chen Z-ME, He L, Sonnenberg GF, Artis D, Fu Y-X, Zhou L. 2013. Group 3 innate lymphoid cells inhibit T-cell-mediated intestinal inflammation through aryl hydrocarbon receptor signaling and regulation of microflora.. Immunity. 39(2):386-99.

Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CGK, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M et al.. 2013. Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.. Nature. 504(7478):153-7.

Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CGK, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M et al.. 2013. Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.. Nature. 504(7478):153-7.

Saenz SA, Siracusa MC, Monticelli LA, Ziegler CGK, Kim BS, Brestoff JR, Peterson LW, E Wherry J, Goldrath AW, Bhandoola A et al.. 2013. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells.. J Exp Med. 210(9):1823-37.

Hepworth MR, Monticelli LA, Fung TC, Ziegler CGK, Grunberg S, Sinha R, Mantegazza AR, Ma H-L, Crawford A, Angelosanto JM et al.. 2013. Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.. Nature. 498(7452):113-7.

Hepworth MR, Monticelli LA, Fung TC, Ziegler CGK, Grunberg S, Sinha R, Mantegazza AR, Ma H-L, Crawford A, Angelosanto JM et al.. 2013. Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.. Nature. 498(7452):113-7.