Submitted by mam2155 on March 24, 2014 - 4:16pm
| Title | Visceral Leishmania donovani infection in interleukin-13-/- mice. |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Murray HW, Tsai CW, Liu J, Ma X |
| Journal | Infect Immun |
| Volume | 74 |
| Issue | 4 |
| Pagination | 2487-90 |
| Date Published | 2006 Apr |
| ISSN | 0019-9567 |
| Keywords | Animals, Cytokines, Immunity, Innate, Interleukin-13, Leishmania donovani, Leishmaniasis, Visceral, Liver Diseases, Parasitic, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout |
| Abstract | Leishmania donovani-infected interleukin-13-/- BALB/c mice showed impaired initial gamma interferon secretion and incomplete granuloma assembly at parasitized liver foci. Nonetheless, control of early parasite replication, resolution of liver infection, and responsiveness to antileishmanial chemotherapy were intact. By itself, interleukin-13 does not appear to materially influence acquired resistance in this intracellular infection. |
| DOI | 10.1128/IAI.74.4.2487-2490.2006 |
| Alternate Journal | Infect Immun |
| PubMed ID | 16552085 |
| PubMed Central ID | PMC1418934 |
| Grant List | R01 AI045899 / AI / NIAID NIH HHS / United States AI 16369 / AI / NIAID NIH HHS / United States AI 45899 / AI / NIAID NIH HHS / United States |