Submitted by mam2155 on March 24, 2014 - 4:14pm
| Title | Resolving resolvases: the final act? |
| Publication Type | Journal Article |
| Year of Publication | 2008 |
| Authors | Symington LS, Holloman WK |
| Journal | Mol Cell |
| Volume | 32 |
| Issue | 5 |
| Pagination | 603-4 |
| Date Published | 2008 Dec 5 |
| ISSN | 1097-4164 |
| Keywords | DNA, Cruciform, HeLa Cells, Humans, Recombinases, Saccharomyces cerevisiae |
| Abstract | The Holliday junction (HJ) is a central intermediate in homologous recombination. Ip et al. (2008), in a recent issue of Nature, have identified a new subclass of the Rad2/XPG family of nucleases with the hallmark of symmetrical cleavage of HJ substrates to produce nicked duplex products. |
| DOI | 10.1016/j.molcel.2008.11.011 |
| Alternate Journal | Mol. Cell |
| PubMed ID | 19061635 |
| Grant List | R01 GM041784-20 / GM / NIGMS NIH HHS / United States R01 GM042482 / GM / NIGMS NIH HHS / United States |