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Found 6 results
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Finzel, Barry C
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2017
Liu F
,
Dawadi S
,
Maize KM
,
Dai R
,
Park SWoong
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2017.
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
.
J Med Chem. 60(13):5507-5520.
2015
Dai R
,
Geders TW
,
Liu F
,
Park SWoong
,
Schnappinger D
,
Aldrich CC
,
Finzel BC
. 2015.
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.
.
J Med Chem. 58(13):5208-17.
Park SWoong
,
Casalena DE
,
Wilson DJ
,
Dai R
,
Nag PP
,
Liu F
,
Boyce JP
,
Bittker JA
,
Schreiber SL
,
Finzel BC
et al.
. 2015.
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.
.
Chem Biol. 22(1):76-86.
Bockman MR
,
Kalinda AS
,
Petrelli R
,
De la Mora-Rey T
,
Tiwari D
,
Liu F
,
Dawadi S
,
Nandakumar M
,
Rhee KY
,
Schnappinger D
et al.
. 2015.
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
.
J Med Chem. 58(18):7349-7369.
2011
Duckworth BP
,
Geders TW
,
Tiwari D
,
Boshoff HI
,
Sibbald PA
,
Barry CE
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2011.
Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis.
.
Chem Biol. 18(11):1432-41.
Shi C
,
Geders TW
,
Park SWoong
,
Wilson DJ
,
Boshoff HI
,
Abayomi O
,
Barry CE
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2011.
Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis.
.
J Am Chem Soc. 133(45):18194-201.