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Found 8 results
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Ioerger, Thomas R
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2019
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
Ballinger E
,
Mosior J
,
Hartman T
,
Burns-Huang K
,
Gold B
,
Morris R
,
Goullieux L
,
Blanc I
,
Vaubourgeix J
,
Lagrange S
et al.
. 2019.
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
.
Science. 363(6426)
Subramaniyam S
,
DeJesus MA
,
Zaveri A
,
Smith CM
,
Baker RE
,
Ehrt S
,
Schnappinger D
,
Sassetti CM
,
Ioerger TR
. 2019.
Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression.
.
BMC Bioinformatics. 20(1):603.
2017
Xu W
,
DeJesus MA
,
Rücker N
,
Engelhart CA
,
Wright MG
,
Healy C
,
Lin K
,
Wang R
,
Park SWoong
,
Ioerger TR
et al.
. 2017.
Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis.
.
Antimicrob Agents Chemother. 61(12)
Puckett S
,
Trujillo C
,
Wang Z
,
Eoh H
,
Ioerger TR
,
Krieger I
,
Sacchettini J
,
Schnappinger D
,
Rhee KY
,
Ehrt S
. 2017.
Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 114(11):E2225-E2232.
2016
Warrier T
,
Kapilashrami K
,
Argyrou A
,
Ioerger TR
,
Little D
,
Murphy KC
,
Nandakumar M
,
Park S
,
Gold B
,
Mi J
et al.
. 2016.
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 113(31):E4523-30.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
2013
Small JL
,
Park SWoong
,
Kana BD
,
Ioerger TR
,
Sacchettini JC
,
Ehrt S
. 2013.
Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis.
.
mBio. 4(5):e00475-13.