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2016
Yan W
,
Ding A
,
Kim H-J
,
Zheng H
,
Wei F
,
Ma X
. 2016.
Progranulin Controls Sepsis via C/EBPα-Regulated Il10 Transcription and Ubiquitin Ligase/Proteasome-Mediated Protein Degradation.
.
J Immunol. 197(8):3393-3405.
Chauhan R
,
Ravi J
,
Datta P
,
Chen T
,
Schnappinger D
,
Bassler KE
,
Balázsi G
,
Gennaro MLaura
. 2016.
Reconstruction and topological characterization of the sigma factor regulatory network of Mycobacterium tuberculosis.
.
Nat Commun. 7:11062.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
2015
Seehus CR
,
Aliahmad P
,
de la Torre B
,
Iliev ID
,
Spurka L
,
Funari VA
,
Kaye J
. 2015.
The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.
.
Nat Immunol. 16(6):599-608.
Ukaegbu UE
,
Deitsch KW
. 2015.
The Emerging Role for RNA Polymerase II in Regulating Virulence Gene Expression in Malaria Parasites.
.
PLoS Pathog. 11(7):e1004926.
Dai R
,
Geders TW
,
Liu F
,
Park SWoong
,
Schnappinger D
,
Aldrich CC
,
Finzel BC
. 2015.
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.
.
J Med Chem. 58(13):5208-17.
de Sena-Tomás C
,
Yu EYoung
,
Calzada A
,
Holloman WK
,
Lue NF
,
Pérez-Martín J
. 2015.
Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres.
.
Nucleic Acids Res. 43(4):2138-51.
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Zhao N
,
Sun M
,
Burns-Huang K
,
Jiang X
,
Ling Y
,
Darby C
,
Ehrt S
,
Liu G
,
Nathan C
. 2015.
Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis.
.
PLoS One. 10(5):e0126211.
Ringe RP
,
Yasmeen A
,
Ozorowski G
,
Go EP
,
Pritchard LK
,
Guttman M
,
Ketas TA
,
Cottrell CA
,
Wilson IA
,
Sanders RW
et al.
. 2015.
Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.
.
J Virol. 89(23):12189-210.
Vaubourgeix J
,
Lin G
,
Dhar N
,
Chenouard N
,
Jiang X
,
Botella H
,
Lupoli T
,
Mariani O
,
Yang G
,
Ouerfelli O
et al.
. 2015.
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.
.
Cell Host Microbe. 17(2):178-90.
Park SWoong
,
Casalena DE
,
Wilson DJ
,
Dai R
,
Nag PP
,
Liu F
,
Boyce JP
,
Bittker JA
,
Schreiber SL
,
Finzel BC
et al.
. 2015.
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.
.
Chem Biol. 22(1):76-86.
Zhao N
,
Darby CM
,
Small J
,
Bachovchin DA
,
Jiang X
,
Burns-Huang KE
,
Botella H
,
Ehrt S
,
Boger DL
,
Anderson ED
et al.
. 2015.
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
.
ACS Chem Biol. 10(2):364-71.
Bockman MR
,
Kalinda AS
,
Petrelli R
,
De la Mora-Rey T
,
Tiwari D
,
Liu F
,
Dawadi S
,
Nandakumar M
,
Rhee KY
,
Schnappinger D
et al.
. 2015.
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
.
J Med Chem. 58(18):7349-7369.
Bockman MR
,
Kalinda AS
,
Petrelli R
,
De la Mora-Rey T
,
Tiwari D
,
Liu F
,
Dawadi S
,
Nandakumar M
,
Rhee KY
,
Schnappinger D
et al.
. 2015.
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
.
J Med Chem. 58(18):7349-7369.
Garg A
,
Wesolowski D
,
Alonso D
,
Deitsch KW
,
Ben Mamoun C
,
Altman S
. 2015.
Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.
.
Proc Natl Acad Sci U S A. 112(38):11935-40.
Ganapathy U
,
Marrero J
,
Calhoun S
,
Eoh H
,
de Carvalho LPedro Sori
,
Rhee K
,
Ehrt S
. 2015.
Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.
.
Nat Commun. 6:7912.
Ukaegbu UE
,
Zhang X
,
Heinberg AR
,
Wele M
,
Chen Q
,
Deitsch KW
. 2015.
A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum.
.
PLoS Genet. 11(5):e1005234.
2014
Sinha A
,
Hughes KR
,
Modrzynska KK
,
Otto TD
,
Pfander C
,
Dickens NJ
,
Religa AA
,
Bushell E
,
Graham AL
,
Cameron R
et al.
. 2014.
A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.
.
Nature. 507(7491):253-257.
Sander AF
,
Lavstsen T
,
Rask TS
,
Lisby M
,
Salanti A
,
Fordyce SL
,
Jespersen JS
,
Carter R
,
Deitsch K
,
Theander TG
et al.
. 2014.
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.
.
Nucleic Acids Res. 42(4):2270-81.
Kirkman L
,
Lawrence EA
,
Deitsch K
. 2014.
Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity.
.
Nucleic Acids Res. 42(1):370-9.
Torgbor C
,
Awuah P
,
Deitsch K
,
Kalantari P
,
Duca KA
,
Thorley-Lawson DA
. 2014.
A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.
.
PLoS Pathog. 10(5):e1004170.
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