Microbiology and Immunology

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2026
Vinette V, Castro A, Kim H, Trujillo C, Xie M, Gengenbacher M, Ioerger TR, Ehrt S.  2026.  Interstitial and recruited macrophages prevent tuberculosis relapse by limiting immune evasion.. EMBO Mol Med.
2025
J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al..  2025.  ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.
J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al..  2025.  ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.
Ohara K, Assaad MAl, McNulty SN, Alnajar H, Sboner A, Wilkes DC, He F, Xiang JZhaoying, Mathew S, Elemento O et al..  2025.  Detection of rare and novel gene fusions in patients with diffuse glioma: An institutional retrospective study.. J Neuropathol Exp Neurol. 84(3):269-271.
Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al..  2025.  A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.
Zhang M, Allen R, Ames L, Engelhart CA, Quach D, Lv X, Xiao G, Wang H, Wang J, Zhou L et al..  2025.  Microbiological evidence for the trisubstituted benzimidazoles targeting MmpL3 in Mycobacterium tuberculosis.. Antimicrob Agents Chemother. :e0036825.
Xu A, Ayoub S, Zhang H, Wu Y, Rau M, Ma X.  2025.  Regulatory T Cells in Invasive Breast Cancer: Prognosis, Mechanisms and Therapy.. Cancers (Basel). 17(19)
Stephanou A, Mantri M, Shankaranarayanan D, Li C, Lagman M, Xiang J, Pan C, Sun Y, Muthukumar T, Machaca K et al..  2025.  Single-cell transcriptomics reveals targeted modulation of inflammatory repertoire by SOCE blockers.. bioRxiv.
Kassegne K, Shen H-M, Chen S-B, Xu S-J, Li J, Xu B, Deitsch KW, Wang Y, Zhou X-N, Chen J-H.  2025.  A subset of Plasmodium falciparum RIFINs is linked to severe malaria risk reduction and engages LILRB1 through a conserved structural motif.. EBioMedicine. 122:106041.
Kassegne K, Shen H-M, Chen S-B, Xu S-J, Li J, Xu B, Deitsch KW, Wang Y, Zhou X-N, Chen J-H.  2025.  A subset of Plasmodium falciparum RIFINs is linked to severe malaria risk reduction and engages LILRB1 through a conserved structural motif.. EBioMedicine. 122:106041.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L et al..  2025.  Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing.. Nat Immunol. 26(3):378-390.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L et al..  2025.  Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing.. Nat Immunol. 26(3):378-390.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L et al..  2025.  Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing.. Nat Immunol. 26(3):378-390.
2024
Caniels TG, Medina-Ramírez M, Zhang S, Kratochvil S, Xian Y, Koo J-H, Derking R, Samsel J, van Schooten J, Pecetta S et al..  2024.  Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site.. Sci Immunol. 9(98):eadk9550.
Chen L, Xu G, Song X, Zhang L, Chen C, Xiang G, Wang S, Zhang Z, Wu F, Yang X et al..  2024.  A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation.. Cancer Lett. 583:216635.
Chen L, Xu G, Song X, Zhang L, Chen C, Xiang G, Wang S, Zhang Z, Wu F, Yang X et al..  2024.  A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation.. Cancer Lett. 583:216635.
Yu Z, Dong X, Song M, Xu A, He Q, Li H, Ouyang W, Chouchane L, Ma X.  2024.  Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.. Int J Cancer. 154(4):723-737.
2023
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al..  2023.  Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.. Nat Commun. 14(1):1756.
Xu Y, Ehrt S, Schnappinger D, Beites T.  2023.  Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation.. mBio. 14(6):e0104523.
2022
Kreutzfeldt KM, Jansen RS, Hartman TE, Gouzy A, Wang R, Krieger IV, Zimmerman MD, Gengenbacher M, Sarathy JP, Xie M et al..  2022.  CinA mediates multidrug tolerance in Mycobacterium tuberculosis.. Nat Commun. 13(1):2203.
Morillo RACampelo, Tong X, Xie W, Abel S, Orchard LM, Daher W, Patel DJ, Llinás M, Le Roch KG, Kafsack BFC.  2022.  The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites.. Nat Microbiol. 7(3):464.
Wu B, Song M, Dong Q, Xiang G, Li J, Ma X, Wei F.  2022.  UBR5 promotes tumor immune evasion through enhancing IFN-γ-induced PDL1 transcription in triple negative breast cancer.. Theranostics. 12(11):5086-5102.
Xiang G, Wang S, Chen L, Song M, Song X, Wang H, Zhou P, Ma X, Yu J.  2022.  UBR5 targets tumor suppressor CDC73 proteolytically to promote aggressive breast cancer.. Cell Death Dis. 13(5):451.
2021
Lee BShi, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMin Sheril, Manimekalai MSony S, Koh VH et al..  2021.  Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.. EMBO Mol Med. 13(1):e13207.
Black KA, Duan L, Mandyoli L, Selbach BP, Xu W, Ehrt S, Sacchettini JC, Rhee KY.  2021.  Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis.. J Exp Med. 218(7)