Microbiology and Immunology

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2021
Calderón F, Fairlamb AH, Strange M, Williams P, Nathan CF.  2021.  Surmounting structural barriers to tackle endemic infectious diseases.. J Exp Med. 218(9)
Yang HS, Racine-Brzostek SE, Karbaschi M, Yee J, Dillard A, Steel PAD, Lee WT, McDonough KA, Qiu Y, Ketas TJ et al..  2021.  Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients.. Biosens Bioelectron. 178:113008.
Yang HS, Racine-Brzostek SE, Karbaschi M, Yee J, Dillard A, Steel PAD, Lee WT, McDonough KA, Qiu Y, Ketas TJ et al..  2021.  Testing-on-a-probe biosensors reveal association of early SARS-CoV-2 total antibodies and surrogate neutralizing antibodies with mortality in COVID-19 patients.. Biosens Bioelectron. 178:113008.
Aldridge BB, Barros-Aguirre D, Barry CE, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu X-J, Cooper CB, Dartois V et al..  2021.  The Tuberculosis Drug Accelerator at year 10: what have we learned? Nat Med. 27(8):1333-1337.
Aldridge BB, Barros-Aguirre D, Barry CE, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu X-J, Cooper CB, Dartois V et al..  2021.  The Tuberculosis Drug Accelerator at year 10: what have we learned? Nat Med. 27(8):1333-1337.
2020
Weskamp G, Tüshaus J, Li D, Feederle R, Maretzky T, Swendemann S, Falck-Pedersen E, McIlwain DR, Mak TW, Salmon JE et al..  2020.  ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).. J Biol Chem. 295(13):4350-4358.
Wang H, Wang C, Peng G, Yu D, Cui X-G, Sun Y-H, Ma X.  2020.  Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.. Mol Cancer Res. 18(2):240-252.
Wang H, Wang C, Peng G, Yu D, Cui X-G, Sun Y-H, Ma X.  2020.  Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.. Mol Cancer Res. 18(2):240-252.
Zaveri A, Wang R, Botella L, Sharma R, Zhu L, Wallach JB, Song N, Jansen RS, Rhee KY, Ehrt S et al..  2020.  Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death.. Mol Microbiol.
Zaveri A, Wang R, Botella L, Sharma R, Zhu L, Wallach JB, Song N, Jansen RS, Rhee KY, Ehrt S et al..  2020.  Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death.. Mol Microbiol.
Moallemian R, Rehman AUr, Zhao N, Wang H, Chen H, Lin G, Ma X, Yu J.  2020.  Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation.. Biochem Pharmacol. 177:113964.
Giardina SF, Werner DS, Pingle M, Feinberg PB, Foreman KW, Bergstrom DE, Arnold LD, Barany F.  2020.  Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase.. J Med Chem. 63(6):3004-3027.
Song M, Wang C, Wang H, Zhang T, Li J, Benezra R, Chouchane L, Sun Y-H, Cui X-G, Ma X.  2020.  Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response.. Oncoimmunology. 9(1):1746148.
Song M, Wang C, Wang H, Zhang T, Li J, Benezra R, Chouchane L, Sun Y-H, Cui X-G, Ma X.  2020.  Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response.. Oncoimmunology. 9(1):1746148.
Gengenbacher M, Zimmerman MD, Sarathy JP, Kaya F, Wang H, Mina M, Carter C, Hossen MAmir, Su H, Trujillo C et al..  2020.  Tissue Distribution of Doxycycline in Animal Models of Tuberculosis.. Antimicrob Agents Chemother. 64(5)
Song M, Yeku OO, Rafiq S, Purdon T, Dong X, Zhu L, Zhang T, Wang H, Yu Z, Mai J et al..  2020.  Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages.. Nat Commun. 11(1):6298.
2019
Ringe RP, Pugach P, Cottrell CA, LaBranche CC, Seabright GE, Ketas TJ, Ozorowski G, Kumar S, Schorcht A, van Gils MJ et al..  2019.  Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.. J Virol. 93(4)
Ringe RP, Pugach P, Cottrell CA, LaBranche CC, Seabright GE, Ketas TJ, Ozorowski G, Kumar S, Schorcht A, van Gils MJ et al..  2019.  Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.. J Virol. 93(4)
Hu W, Zi Z, Jin Y, Li G, Shao K, Cai Q, Ma X, Wei F.  2019.  CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions.. Cancer Immunol Immunother. 68(3):365-377.
Wu J, Mu R, Sun M, Zhao N, Pan M, Li H, Dong Y, Sun Z, Bai J, Hu M et al..  2019.  Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .. ACS Infect Dis. 5(7):1087-1104.
Wang C, Li Y, Chu C-M, Zhang X-M, Ma J, Huang H, Wang Y-N, Hong T-Y, Zhang J, Pan X-W et al..  2019.  Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma.. EBioMedicine. 39:255-264.
Wang C, Li Y, Chu C-M, Zhang X-M, Ma J, Huang H, Wang Y-N, Hong T-Y, Zhang J, Pan X-W et al..  2019.  Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma.. EBioMedicine. 39:255-264.
Early J, Ollinger J, Darby C, Alling T, Mullen S, Casey A, Gold B, Ochoada J, Wiernicki T, Masquelin T et al..  2019.  Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.. ACS Infect Dis. 5(2):272-280.
Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong T-T et al..  2019.  Improvement of Asparagine Ethylenediamines as Anti-malarial -Selective Proteasome Inhibitors.. J Med Chem. 62(13):6137-6145.
Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong T-T et al..  2019.  Improvement of Asparagine Ethylenediamines as Anti-malarial -Selective Proteasome Inhibitors.. J Med Chem. 62(13):6137-6145.