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2026
Hunt DM, Pisco JPedro, Rodgers A, de Chiara C, Zaveri A, Pacholarz KL, Evangelopoulos D, Garza-Garcia A, Ehrt S, Schnappinger D et al.
. 2026.
Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis.
.
Nat Commun. 17(1)
Seshadri C, Flynn JAL, Maiello P, Schnappinger D, Wilkinson RJ, Gordon SB, Mwandumba HC, Jambo KC, Hoft DF, Rubin EJ et al.
. 2026.
Controlled human infection with Mycobacterium tuberculosis: practical considerations for clinical trials.
.
Lancet Microbe. :101278.
Seshadri C, Flynn JAL, Maiello P, Schnappinger D, Wilkinson RJ, Gordon SB, Mwandumba HC, Jambo KC, Hoft DF, Rubin EJ et al.
. 2026.
Controlled human infection with Mycobacterium tuberculosis: practical considerations for clinical trials.
.
Lancet Microbe. :101278.
Sarkar A, Schwer B, Shuman S
. 2026.
Fission yeast Tpt1 is composed of tandem RNA 2'-phosphotransferase and Yae1 domains, both of which are essential for viability.
.
RNA. 32(2):237-249.
Sarkar A, Schwer B, Shuman S
. 2026.
Fission yeast Tpt1 is composed of tandem RNA 2'-phosphotransferase and Yae1 domains, both of which are essential for viability.
.
RNA. 32(2):237-249.
Sarkar A, Schwer B, Shuman S
. 2026.
Fission yeast Tpt1 is composed of tandem RNA 2'-phosphotransferase and Yae1 domains, both of which are essential for viability.
.
RNA. 32(2):237-249.
Innokentev A, Schwer B, Shuman S
. 2026.
Ifn1 is an intracellular GMP 5'-nucleotidase induced during the fission yeast response to phosphate starvation.
.
mBio. 17(4):e0394225.
Innokentev A, Schwer B, Shuman S
. 2026.
Ifn1 is an intracellular GMP 5'-nucleotidase induced during the fission yeast response to phosphate starvation.
.
mBio. 17(4):e0394225.
Schnappinger D, Berthel SJ, Boshoff HIM, Krieger IV, Sukheja P, Panda S, Rath S, Briggs K, Bian X, Rasheed S et al.
. 2026.
Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.
.
EMBO Mol Med.
Schnappinger D, Berthel SJ, Boshoff HIM, Krieger IV, Sukheja P, Panda S, Rath S, Briggs K, Bian X, Rasheed S et al.
. 2026.
Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.
.
EMBO Mol Med.
Schnappinger D, Berthel SJ, Boshoff HIM, Krieger IV, Sukheja P, Panda S, Rath S, Briggs K, Bian X, Rasheed S et al.
. 2026.
Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.
.
EMBO Mol Med.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T
. 2026.
Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.
.
Commun Biol.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T
. 2026.
Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.
.
Commun Biol.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T
. 2026.
Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.
.
Commun Biol.
Klevorn T, Brown C, Hardy CD, Cuthbert BJ, Spencer A, Jinich A, Chan L, Angala SK, Manzer J, Mendoza J et al.
. 2026.
A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis.
.
Sci Adv. 12(14):eaec5100.
Klevorn T, Brown C, Hardy CD, Cuthbert BJ, Spencer A, Jinich A, Chan L, Angala SK, Manzer J, Mendoza J et al.
. 2026.
A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis.
.
Sci Adv. 12(14):eaec5100.
Courbon GM, Makarov V, Cole ST, Schnapinger D, Ehrt S, Rubinstein JL
. 2026.
Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria.
.
EMBO J. 45(8):2785-2807.
Khonde LPeguy, Peton N, Masike K, Valentine T, Zindo F, Fienberg S, Omollo C, Njoroge M, Vallini F, Tammaro C et al.
. 2026.
Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors.
.
Eur J Med Chem. 312:118841.
Khonde LPeguy, Peton N, Masike K, Valentine T, Zindo F, Fienberg S, Omollo C, Njoroge M, Vallini F, Tammaro C et al.
. 2026.
Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors.
.
Eur J Med Chem. 312:118841.
Hrach VLee, Schwer B, Vitek L, Borowicz M, Innokentev A, Sanchez AM, Singer JR, Shuman S, Patton-Vogt J
. 2026.
Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast.
.
Biomolecules. 16(2)
Hrach VLee, Schwer B, Vitek L, Borowicz M, Innokentev A, Sanchez AM, Singer JR, Shuman S, Patton-Vogt J
. 2026.
Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast.
.
Biomolecules. 16(2)
Hrach VLee, Schwer B, Vitek L, Borowicz M, Innokentev A, Sanchez AM, Singer JR, Shuman S, Patton-Vogt J
. 2026.
Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast.
.
Biomolecules. 16(2)
Hrach VLee, Schwer B, Vitek L, Borowicz M, Innokentev A, Sanchez AM, Singer JR, Shuman S, Patton-Vogt J
. 2026.
Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast.
.
Biomolecules. 16(2)
2025
Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W et al.
. 2025.
AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.
.
Sci Adv. 11(34):eadv6937.
Du Y, Faz-Lopez B, Kioon MDominique, Cenac C, Pierides M, Lakin KS, Spiera RF, Chaumeil J, Truchetet M-E, Gordon JK et al.
. 2025.
Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis.
.
J Exp Med. 222(3)
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