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2026
Hunt DM, Pisco JPedro, Rodgers A, de Chiara C, Zaveri A, Pacholarz KL, Evangelopoulos D, Garza-Garcia A, Ehrt S, Schnappinger D et al..  2026.  Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis.. Nat Commun. 17(1)
Seshadri C, Flynn JAL, Maiello P, Schnappinger D, Wilkinson RJ, Gordon SB, Mwandumba HC, Jambo KC, Hoft DF, Rubin EJ et al..  2026.  Controlled human infection with Mycobacterium tuberculosis: practical considerations for clinical trials.. Lancet Microbe. :101278.
Seshadri C, Flynn JAL, Maiello P, Schnappinger D, Wilkinson RJ, Gordon SB, Mwandumba HC, Jambo KC, Hoft DF, Rubin EJ et al..  2026.  Controlled human infection with Mycobacterium tuberculosis: practical considerations for clinical trials.. Lancet Microbe. :101278.
Liu Q, Engelhart CA, Wallach JB, Ge P, Wong T-Y, Orimoloye MO, Rodriguez S, Jayasinghe YP, Ronning DR, Dartois V et al..  2026.  Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem.
Liu Q, Engelhart CA, Wallach JB, Ge P, Wong T-Y, Orimoloye MO, Rodriguez S, Jayasinghe YP, Ronning DR, Dartois V et al..  2026.  Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem.
Sarkar A, Schwer B, Shuman S.  2026.  Fission yeast Tpt1 is composed of tandem RNA 2'-phosphotransferase and Yae1 domains, both of which are essential for viability.. RNA. 32(2):237-249.
Sarkar A, Schwer B, Shuman S.  2026.  Fission yeast Tpt1 is composed of tandem RNA 2'-phosphotransferase and Yae1 domains, both of which are essential for viability.. RNA. 32(2):237-249.
Sarkar A, Schwer B, Shuman S.  2026.  Fission yeast Tpt1 is composed of tandem RNA 2'-phosphotransferase and Yae1 domains, both of which are essential for viability.. RNA. 32(2):237-249.
Babor J, Sanchez AM, Prucker I, Jessen HJ, Schwer B, Shuman S.  2026.  How interdiction of inositol pyrophosphate catabolism perturbs the fission yeast response to phosphate starvation.. Nucleic Acids Res. 54(8)
Babor J, Sanchez AM, Prucker I, Jessen HJ, Schwer B, Shuman S.  2026.  How interdiction of inositol pyrophosphate catabolism perturbs the fission yeast response to phosphate starvation.. Nucleic Acids Res. 54(8)
Babor J, Sanchez AM, Prucker I, Jessen HJ, Schwer B, Shuman S.  2026.  How interdiction of inositol pyrophosphate catabolism perturbs the fission yeast response to phosphate starvation.. Nucleic Acids Res. 54(8)
Innokentev A, Schwer B, Shuman S.  2026.  Ifn1 is an intracellular GMP 5'-nucleotidase induced during the fission yeast response to phosphate starvation.. mBio. 17(4):e0394225.
Innokentev A, Schwer B, Shuman S.  2026.  Ifn1 is an intracellular GMP 5'-nucleotidase induced during the fission yeast response to phosphate starvation.. mBio. 17(4):e0394225.
Schnappinger D, Berthel SJ, Boshoff HIM, Krieger IV, Sukheja P, Panda S, Rath S, Briggs K, Bian X, Rasheed S et al..  2026.  Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.. EMBO Mol Med.
Schnappinger D, Berthel SJ, Boshoff HIM, Krieger IV, Sukheja P, Panda S, Rath S, Briggs K, Bian X, Rasheed S et al..  2026.  Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.. EMBO Mol Med.
Schnappinger D, Berthel SJ, Boshoff HIM, Krieger IV, Sukheja P, Panda S, Rath S, Briggs K, Bian X, Rasheed S et al..  2026.  Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.. EMBO Mol Med.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T.  2026.  Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.. Commun Biol.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T.  2026.  Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.. Commun Biol.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T.  2026.  Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.. Commun Biol.
Klevorn T, Brown C, Hardy CD, Cuthbert BJ, Spencer A, Jinich A, Chan L, Angala SK, Manzer J, Mendoza J et al..  2026.  A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis.. Sci Adv. 12(14):eaec5100.
Klevorn T, Brown C, Hardy CD, Cuthbert BJ, Spencer A, Jinich A, Chan L, Angala SK, Manzer J, Mendoza J et al..  2026.  A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis.. Sci Adv. 12(14):eaec5100.
Courbon GM, Makarov V, Cole ST, Schnapinger D, Ehrt S, Rubinstein JL.  2026.  Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria.. EMBO J. 45(8):2785-2807.
Khonde LPeguy, Peton N, Masike K, Valentine T, Zindo F, Fienberg S, Omollo C, Njoroge M, Vallini F, Tammaro C et al..  2026.  Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors.. Eur J Med Chem. 312:118841.
Khonde LPeguy, Peton N, Masike K, Valentine T, Zindo F, Fienberg S, Omollo C, Njoroge M, Vallini F, Tammaro C et al..  2026.  Structure-Activity relationship and optimization of drug-like properties of antituberculosis 3-(4,4-dimethyl-1,4-azasilinane)methylpyrazole MmpL3 inhibitors.. Eur J Med Chem. 312:118841.
Hrach VLee, Schwer B, Vitek L, Borowicz M, Innokentev A, Sanchez AM, Singer JR, Shuman S, Patton-Vogt J.  2026.  Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast.. Biomolecules. 16(2)