Microbiology and Immunology

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2023
Zhan W, Li D, Subramanyaswamy SBevkal, Liu YJing, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H et al..  2023.  Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.. Cell Chem Biol. 30(5):457-469.e11.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al..  2023.  Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.. Cell Rep Med. 4(4):101003.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al..  2023.  Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.. Cell Rep Med. 4(4):101003.
Caniels TG, Medina-Ramírez M, Zhang J, Sarkar A, Kumar S, LaBranche A, Derking R, Allen JD, Snitselaar JL, Capella-Pujol J et al..  2023.  Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions.. Cell Rep Med. 4(4):101003.
Ringe RP, Colin P, Ozorowski G, Allen JD, Yasmeen A, Seabright GE, Lee JHyun, Antanasijevic A, Rantalainen K, Ketas T et al..  2023.  Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization.. PLoS Pathog. 19(10):e1011601.
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al..  2023.  Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.. Nat Commun. 14(1):1756.
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al..  2023.  Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.. Nat Commun. 14(1):1756.
Li F, Wang Y, Hwang I, Jang J-Y, Xu L, Deng Z, Yu EYoung, Cai Y, Wu C, Han Z et al..  2023.  Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance.. Nat Commun. 14(1):1756.
Capucci S, Wee EG, Schiffner T, LaBranche CC, Borthwick N, Cupo A, Dodd J, Dean H, Sattentau Q, Montefiori D et al..  2023.  HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers.. PLoS One. 18(10):e0293148.
Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al..  2023.  Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.. J Med Chem. 66(22):15380-15408.
Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al..  2023.  Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.. J Med Chem. 66(22):15380-15408.
Sharma I, Fang J, Lewallen EA, Deitsch KW, McCutchan TF.  2023.  Identification of a long noncoding RNA required for temperature induced expression of stage-specific rRNA in malaria parasites.. Gene. 877:147516.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al..  2023.  Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.. Nucleic Acids Res. 51(2):668-686.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al..  2023.  Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.. Nucleic Acids Res. 51(2):668-686.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al..  2023.  Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.. Nucleic Acids Res. 51(2):668-686.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D et al..  2023.  Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.. ACS Med Chem Lett. 14(7):970-976.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D et al..  2023.  Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.. ACS Med Chem Lett. 14(7):970-976.
Lue NF, Autexier C.  2023.  Orchestrating nucleic acid-protein interactions at chromosome ends: telomerase mechanisms come into focus.. Nat Struct Mol Biol. 30(7):878-890.
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H.  2023.  Structure of the human UBR5 E3 ubiquitin ligase.. Structure. 31(5):541-552.e4.
Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H.  2023.  Structure of the human UBR5 E3 ubiquitin ligase.. Structure. 31(5):541-552.e4.
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2023.  Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2023.  Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2023.  Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al..  2023.  Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.
Hsu H-C, Li D, Zhan W, Ye J, Liu YJing, Leung A, Qin J, Crespo B, Gamo F-J, Zhang H et al..  2023.  Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium falciparum to proteasome inhibitors.. Nat Commun. 14(1):8302.