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2024
Krieger IV, Yalamanchili S, Dickson P, Engelhart CA, Zimmerman MD, Wood J, Clary E, Nguyen J, Thornton N, Centrella PA et al..  2024.  Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.. ACS Infect Dis. 10(5):1561-1575.
Qu D, Ge P, Botella L, Park SWoong, Lee H-N, Thornton N, Bean JM, Krieger IV, Sacchettini JC, Ehrt S et al..  2024.  Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin.. Nat Commun. 15(1):4161.
Dupnik K, Rivera VR, Dorvil N, Duffus Y, Akbarnejad H, Gao Y, Liu J, Apollon A, Dumont E, Riviere C et al..  2024.  Potential Utility of C-reactive Protein for Tuberculosis Risk Stratification Among Patients With Non-Meningitic Symptoms at HIV Diagnosis in Low- and Middle-income Countries.. Open Forum Infect Dis. 11(7):ofae356.
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al..  2024.  Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al..  2024.  Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.
Singh A, Ottavi S, Krieger I, Planck K, Perkowski A, Kaneko T, Davis AM, Suh C, Zhang D, Goullieux L et al..  2024.  Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase.. Sci Adv. 10(11):eadj6406.
Schwer B, Innokentev A, Sanchez AM, Garg A, Shuman S.  2024.  Suppression of inositol pyrophosphate toxicosis and hyper-repression of the fission yeast PHO regulon by loss-of-function mutations in chromatin remodelers Snf22 and Sol1.. mBio. 15(7):e0125224.
Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al..  2024.  Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.
Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al..  2024.  Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.
Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al..  2024.  Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.
Song M, Huang S, Wu X, Zhao Z, Liu X, Wu C, Wang M, Gao J, Ke Z, Ma X et al..  2024.  UBR5 mediates colorectal cancer chemoresistance by attenuating ferroptosis via Lys 11 ubiquitin-dependent stabilization of Smad3-SLC7A11 signaling.. Redox Biol. 76:103349.
2023
Garg A, Sanchez AM, Miele M, Schwer B, Shuman S.  2023.  Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.. Nucleic Acids Res. 51(7):3094-3115.
de Miranda R, Cuthbert BJ, Klevorn T, Chao A, Mendoza J, Arbing M, Sieminski PJ, Papavinasasundaram K, Abdul-Hafiz S, Chan S et al..  2023.  Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake.. PLoS Pathog. 19(9):e1011650.
Sanchez AM, Garg A, Schwer B, Shuman S.  2023.  Duf89 abets lncRNA control of fission yeast phosphate homeostasis via its antagonism of precocious lncRNA transcription termination.. RNA. 29(6):808-825.
Garg A, Schwer B, Shuman S.  2023.  Fission yeast poly(A) polymerase active site mutation Y86D alleviates the rad24Δ asp1-H397A synthetic growth defect and up-regulates mRNAs targeted by MTREC and Mmi1.. RNA. 29(11):1738-1753.
Schneider VM, Visone JE, Harris CT, Florini F, Hadjimichael E, Zhang X, Gross MR, Rhee KY, Ben Mamoun C, Kafsack BFC et al..  2023.  The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching.. Proc Natl Acad Sci U S A. 120(17):e2302152120.
Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al..  2023.  Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.. J Med Chem. 66(22):15380-15408.
Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al..  2023.  Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.. J Med Chem. 66(22):15380-15408.
Sanchez AM, Garg A, Schwer B, Shuman S.  2023.  Inorganic polyphosphate abets silencing of a sub-telomeric gene cluster in fission yeast.. MicroPubl Biol. 2023
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al..  2023.  Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.. Nucleic Acids Res. 51(2):668-686.
Coloma J, Gonzalez-Rodriguez N, Balaguer FA, Gmurczyk K, Aicart-Ramos C, Nuero ÓM, Luque-Ortega JRomán, Calugaru K, Lue NF, Moreno-Herrero F et al..  2023.  Molecular architecture and oligomerization of Candida glabrata Cdc13 underpin its telomeric DNA-binding and unfolding activity.. Nucleic Acids Res. 51(2):668-686.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D et al..  2023.  Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.. ACS Med Chem Lett. 14(7):970-976.
Ottavi S, Li K, Cacioppo JG, Perkowski AJ, Ramesh R, Gold BS, Ling Y, Roberts J, Singh A, Zhang D et al..  2023.  Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas.. ACS Med Chem Lett. 14(7):970-976.
Gui W, Giardina SF, Balzarini M, Barany F, Kodadek T.  2023.  Reversible Assembly of Proteolysis Targeting Chimeras.. ACS Chem Biol. 18(7):1582-1593.
Gui W, Giardina SF, Balzarini M, Barany F, Kodadek T.  2023.  Reversible Assembly of Proteolysis Targeting Chimeras.. ACS Chem Biol. 18(7):1582-1593.