Microbiology and Immunology

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2007
Gandotra S, Schnappinger D, Monteleone M, Hillen W, Ehrt S.  2007.  In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.. Nat Med. 13(12):1515-20.
Deitsch K, Duraisingh M, Dzikowski R, Gunasekera A, Khan S, Le Roch K, Llinás M, Mair G, McGovern V, Roos D et al..  2007.  Mechanisms of gene regulation in Plasmodium.. Am J Trop Med Hyg. 77(2):201-8.
Pingle MR, Granger K, Feinberg P, Shatsky R, Sterling B, Rundell M, Spitzer E, Larone D, Golightly LM, Barany F.  2007.  Multiplexed identification of blood-borne bacterial pathogens by use of a novel 16S rRNA gene PCR-ligase detection reaction-capillary electrophoresis assay.. J Clin Microbiol. 45(6):1927-35.
Pingle MR, Granger K, Feinberg P, Shatsky R, Sterling B, Rundell M, Spitzer E, Larone D, Golightly LM, Barany F.  2007.  Multiplexed identification of blood-borne bacterial pathogens by use of a novel 16S rRNA gene PCR-ligase detection reaction-capillary electrophoresis assay.. J Clin Microbiol. 45(6):1927-35.
Stephanou NC, Gao F, Bongiorno P, Ehrt S, Schnappinger D, Shuman S, Glickman MS.  2007.  Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.. J Bacteriol. 189(14):5237-46.
Stephanou NC, Gao F, Bongiorno P, Ehrt S, Schnappinger D, Shuman S, Glickman MS.  2007.  Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.. J Bacteriol. 189(14):5237-46.
Werts C, le Bourhis L, Liu J, Magalhaes JG, Carneiro LA, Fritz JH, Stockinger S, Balloy V, Chignard M, Decker T et al..  2007.  Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.. Eur J Immunol. 37(9):2499-508.
Gandotra S, Jang S, Murray PJ, Salgame P, Ehrt S.  2007.  Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.. Infect Immun. 75(11):5127-34.
Liu J, Guan X, Ma X.  2007.  Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways.. J Exp Med. 204(1):141-52.
Guo XV, Monteleone M, Klotzsche M, Kamionka A, Hillen W, Braunstein M, Ehrt S, Schnappinger D.  2007.  Silencing Mycobacterium smegmatis by using tetracycline repressors.. J Bacteriol. 189(13):4614-23.
Gao H, Huang J, Barany F, Cao W.  2007.  Switching base preferences of mismatch cleavage in endonuclease V: an improved method for scanning point mutations.. Nucleic Acids Res. 35(1):e2.
2006
Tripathi P, Madan R, Chougnet C, Divanovic S, Ma X, Wahl LM, Gajewski T, Karp CL, Hildeman DA.  2006.  An adenoviral vector for probing promoter activity in primary immune cells.. J Immunol Methods. 311(1-2):19-30.
Vandal OH, Gelb MH, Ehrt S, Nathan CF.  2006.  Cytosolic phospholipase A2 enzymes are not required by mouse bone marrow-derived macrophages for the control of Mycobacterium tuberculosis in vitro.. Infect Immun. 74(3):1751-6.
Tsafrir D, Bacolod M, Selvanayagam Z, Tsafrir I, Shia J, Zeng Z, Liu H, Krier C, Stengel RF, Barany F et al..  2006.  Relationship of gene expression and chromosomal abnormalities in colorectal cancer.. Cancer Res. 66(4):2129-37.
2005
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Murray HW, Flanders KC, Donaldson DD, Sypek JP, Gotwals PJ, Liu J, Ma X.  2005.  Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis.. Infect Immun. 73(7):3903-11.
Favis R, Gerry NP, Cheng Y-W, Barany F.  2005.  Applications of the universal DNA microarray in molecular medicine.. Methods Mol Med. 114:25-58.
Ehrt S, Guo XV, Hickey CM, Ryou M, Monteleone M, Riley LW, Schnappinger D.  2005.  Controlling gene expression in mycobacteria with anhydrotetracycline and Tet repressor.. Nucleic Acids Res. 33(2):e21.
Shi S, Blumenthal A, Hickey CM, Gandotra S, Levy D, Ehrt S.  2005.  Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.. J Immunol. 175(5):3318-28.
Hisert KB, MacCoss M, Shiloh MU, K Darwin H, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S et al..  2005.  A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.. Mol Microbiol. 56(5):1234-45.
Hisert KB, MacCoss M, Shiloh MU, K Darwin H, Singh S, Jones RA, Ehrt S, Zhang Z, Gaffney BL, Gandotra S et al..  2005.  A glutamate-alanine-leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.. Mol Microbiol. 56(5):1234-45.
Liu J, Guan X, Ma X.  2005.  Interferon regulatory factor 1 is an essential and direct transcriptional activator for interferon {gamma}-induced RANTES/CCl5 expression in macrophages.. J Biol Chem. 280(26):24347-55.
Liu J, Cao S, Kim S, Chung EY, Homma Y, Guan X, Jimenez V, Ma X.  2005.  Interleukin-12: an update on its immunological activities, signaling and regulation of gene expression.. Curr Immunol Rev. 1(2):119-137.
Gannoun-Zaki L, Jost A, Mu J, Deitsch KW, Wellems TE.  2005.  A silenced Plasmodium falciparum var promoter can be activated in vivo through spontaneous deletion of a silencing element in the intron.. Eukaryot Cell. 4(2):490-2.
Shan D, Chen L, Njardarson JT, Gaul C, Ma X, Danishefsky SJ, Huang X-Y.  2005.  Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.. Proc Natl Acad Sci U S A. 102(10):3772-6.