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Found 253 results
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2026
Hunt DM, Pisco JPedro, Rodgers A, de Chiara C, Zaveri A, Pacholarz KL, Evangelopoulos D, Garza-Garcia A, Ehrt S, Schnappinger D et al..  2026.  Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis.. Nat Commun. 17(1)
Hunt DM, Pisco JPedro, Rodgers A, de Chiara C, Zaveri A, Pacholarz KL, Evangelopoulos D, Garza-Garcia A, Ehrt S, Schnappinger D et al..  2026.  Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis.. Nat Commun. 17(1)
Tsai C-Y, Xie M, Cristaldo M, Peluso GR, Woo J, Nuritdinov F, Odjourian NM, Dougher M, Antilus-Sainte R, Kreutzfeldt KM et al..  2026.  BCG vaccination with adjunctive APRIL immunotherapy reduces tuberculosis relapse in mice.. J Infect Dis.
Liu Q, Engelhart CA, Wallach JB, Ge P, Wong T-Y, Orimoloye MO, Rodriguez S, Jayasinghe YP, Ronning DR, Dartois V et al..  2026.  Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem.
Vinette V, Castro A, Kim H, Trujillo C, Xie M, Gengenbacher M, Ioerger TR, Ehrt S.  2026.  Interstitial and recruited macrophages prevent tuberculosis relapse by limiting immune evasion.. EMBO Mol Med.
Moses A, Zhang A, Todorovic M, Ramakrishna R, Facciani M, Eagleman DM, Sever R, Eyre HA, Bhamla S, Moore JP et al..  2026.  Modern science outreach: A guide for scientists.. Cell. 189(17):5174-5181.
Moses A, Zhang A, Todorovic M, Ramakrishna R, Facciani M, Eagleman DM, Sever R, Eyre HA, Bhamla S, Moore JP et al..  2026.  Modern science outreach: A guide for scientists.. Cell. 189(17):5174-5181.
Pinto AJ, Silva M, Santos JA, VanderVen BC, Monteiro R, Schnappinger D, Ehrt S, Beites T.  2026.  Mycobacterium tuberculosis long-chain fatty acid resistome reveals universal stress protein TB15.3 as essential for infection.. Commun Biol.
Klevorn T, Brown C, Hardy CD, Cuthbert BJ, Spencer A, Jinich A, Chan L, Angala SK, Manzer J, Mendoza J et al..  2026.  A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosis.. Sci Adv. 12(14):eaec5100.
Courbon GM, Makarov V, Cole ST, Schnapinger D, Ehrt S, Rubinstein JL.  2026.  Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria.. EMBO J. 45(8):2785-2807.
Marks F, Lilic M, Nalam P, Mclelland L, An X, Fortune SM, Campbell EA, Ehrt S.  2026.  The WhiA and WhiB2 transcription factors mediate the Mycobacterium tuberculosis cell cycle by regulating DNA replication and cell division.. NAR Mol Med. 3(3):ugag039.
2025
Smith AA, Su H, Wallach J, Liu Y, Maiello P, H Borish J, Winchell C, Simonson AW, Lin PLing, Rodgers M et al..  2025.  A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity.. Nat Microbiol. 10(2):468-481.
J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al..  2025.  ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.
Ames L, Allen R, Boshoff HIM, Cleghorn LAT, Engelhart CA, Schnappinger D, Parish T.  2025.  Common Biological Properties of Mycobacterium tuberculosis MmpL3 Inhibitors.. ACS Infect Dis.
Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al..  2025.  Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.
Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al..  2025.  Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.
Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al..  2025.  Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.
Ohara K, Assaad MAl, McNulty SN, Alnajar H, Sboner A, Wilkes DC, He F, Xiang JZhaoying, Mathew S, Elemento O et al..  2025.  Detection of rare and novel gene fusions in patients with diffuse glioma: An institutional retrospective study.. J Neuropathol Exp Neurol. 84(3):269-271.
Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K et al..  2025.  Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.. Nat Microbiol. 10(2):482-494.
Healy C, Ehrt S, Gouzy A.  2025.  An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH.. mBio. 16(1):e0282524.
Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al..  2025.  A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.
Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al..  2025.  Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.
Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al..  2025.  Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.
Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al..  2025.  Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.
Healy C, Ioerger TR, Ehrt S, Gouzy A.  2025.  Identifying genetic determinants of Mycobacterium tuberculosis acid growth arrest by transposon mutagenesis coupled with next-generation sequencing (Tn-seq).. Microbiol Resour Announc. 14(8):e0006025.