Microbiology and Immunology

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Found 422 results

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2015

Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW et al.. 2015. Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.. J Virol. 89(23):12189-210.

Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O et al.. 2015. Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.. Cell Host Microbe. 17(2):178-90.

Park SWoong, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC et al.. 2015. Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.. Chem Biol. 22(1):76-86.

Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED et al.. 2015. Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.. ACS Chem Biol. 10(2):364-71.

Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al.. 2015. Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.

Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al.. 2015. Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.

Garg A, Wesolowski D, Alonso D, Deitsch KW, Ben Mamoun C, Altman S. 2015. Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.. Proc Natl Acad Sci U S A. 112(38):11935-40.

Ganapathy U, Marrero J, Calhoun S, Eoh H, de Carvalho LPedro Sori, Rhee K, Ehrt S. 2015. Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.. Nat Commun. 6:7912.

Ukaegbu UE, Zhang X, Heinberg AR, Wele M, Chen Q, Deitsch KW. 2015. A Unique Virulence Gene Occupies a Principal Position in Immune Evasion by the Malaria Parasite Plasmodium falciparum.. PLoS Genet. 11(5):e1005234.

2014

Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R et al.. 2014. A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.. Nature. 507(7491):253-257.

Sander AF, Lavstsen T, Rask TS, Lisby M, Salanti A, Fordyce SL, Jespersen JS, Carter R, Deitsch K, Theander TG et al.. 2014. DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.. Nucleic Acids Res. 42(4):2270-81.

Kirkman L, Lawrence EA, Deitsch K. 2014. Malaria parasites utilize both homologous recombination and alternative end joining pathways to maintain genome integrity.. Nucleic Acids Res. 42(1):370-9.

Torgbor C, Awuah P, Deitsch K, Kalantari P, Duca KA, Thorley-Lawson DA. 2014. A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.. PLoS Pathog. 10(5):e1004170.

Torgbor C, Awuah P, Deitsch K, Kalantari P, Duca KA, Thorley-Lawson DA. 2014. A multifactorial role for P. falciparum malaria in endemic Burkitt's lymphoma pathogenesis.. PLoS Pathog. 10(5):e1004170.

Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Di Wu T-, Poincloux R et al.. 2014. Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.. PLoS Pathog. 10(2):e1003928.

Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Di Wu T-, Poincloux R et al.. 2014. Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.. PLoS Pathog. 10(2):e1003928.

Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Di Wu T-, Poincloux R et al.. 2014. Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.. PLoS Pathog. 10(2):e1003928.

Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Di Wu T-, Poincloux R et al.. 2014. Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.. PLoS Pathog. 10(2):e1003928.

Danilchanka O, Sun J, Pavlenok M, Maueröder C, Speer A, Siroy A, Marrero J, Trujillo C, Mayhew DL, Doornbos KS et al.. 2014. An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.. Proc Natl Acad Sci U S A. 111(18):6750-5.

Danilchanka O, Sun J, Pavlenok M, Maueröder C, Speer A, Siroy A, Marrero J, Trujillo C, Mayhew DL, Doornbos KS et al.. 2014. An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.. Proc Natl Acad Sci U S A. 111(18):6750-5.

Coleman BI, Skillman KM, H Y Jiang R, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M et al.. 2014. A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.. Cell Host Microbe. 16(2):177-186.

Ukaegbu UE, Kishore SP, Kwiatkowski DL, Pandarinath C, Dahan-Pasternak N, Dzikowski R, Deitsch K. 2014. Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.. PLoS Pathog. 10(1):e1003854.

Ukaegbu UE, Kishore SP, Kwiatkowski DL, Pandarinath C, Dahan-Pasternak N, Dzikowski R, Deitsch K. 2014. Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.. PLoS Pathog. 10(1):e1003854.

Ukaegbu UE, Kishore SP, Kwiatkowski DL, Pandarinath C, Dahan-Pasternak N, Dzikowski R, Deitsch K. 2014. Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.. PLoS Pathog. 10(1):e1003854.

Kafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA et al.. 2014. A transcriptional switch underlies commitment to sexual development in malaria parasites.. Nature. 507(7491):248-52.