Microbiology and Immunology

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2022
Govender P, Müller R, Singh K, Reddy V, Eyermann CJ, Fienberg S, Ghorpade SR, Koekemoer L, Myrick A, Schnappinger D et al..  2022.  Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.. J Med Chem. 65(9):6903-6925.
Xiang G, Wang S, Chen L, Song M, Song X, Wang H, Zhou P, Ma X, Yu J.  2022.  UBR5 targets tumor suppressor CDC73 proteolytically to promote aggressive breast cancer.. Cell Death Dis. 13(5):451.
2021
van Haaren MM, McCoy LE, Torres JL, Lee W, Cottrell CA, Copps JL, van der Woude P, Yasmeen A, de Taeye SW, A de la Peña T et al..  2021.  Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein.. J Virol. 95(17):e0009421.
van Haaren MM, McCoy LE, Torres JL, Lee W, Cottrell CA, Copps JL, van der Woude P, Yasmeen A, de Taeye SW, A de la Peña T et al..  2021.  Antibodies from Rabbits Immunized with HIV-1 Clade B SOSIP Trimers Can Neutralize Multiple Clade B Viruses by Destabilizing the Envelope Glycoprotein.. J Virol. 95(17):e0009421.
van Schooten J, van Haaren MM, Li H, McCoy LE, Havenar-Daughton C, Cottrell CA, Burger JA, van der Woude P, Helgers LC, Tomris I et al..  2021.  Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.. PLoS Pathog. 17(8):e1009736.
van Schooten J, van Haaren MM, Li H, McCoy LE, Havenar-Daughton C, Cottrell CA, Burger JA, van der Woude P, Helgers LC, Tomris I et al..  2021.  Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.. PLoS Pathog. 17(8):e1009736.
Ketas TJ, Chaturbhuj D, Portillo VMCruz, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD et al..  2021.  Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.. Pathog Immun. 6(1):116-134.
Ketas TJ, Chaturbhuj D, Portillo VMCruz, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD et al..  2021.  Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.. Pathog Immun. 6(1):116-134.
Ketas TJ, Chaturbhuj D, Portillo VMCruz, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD et al..  2021.  Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.. Pathog Immun. 6(1):116-134.
Ketas TJ, Chaturbhuj D, Portillo VMCruz, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD et al..  2021.  Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.. Pathog Immun. 6(1):116-134.
de Melo CSoares, Singh V, Myrick A, Simelane SB, Taylor D, Brunschwig C, Lawrence N, Schnappinger D, Engelhart CA, Kumar A et al..  2021.  Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies.. J Med Chem. 64(1):719-740.
Wang C, Hong TY, Wang Y, Peng G, Yu Y, Zhang J, Zhuo D, Zheng J, Ma X, Cui X.  2021.  Combining UBR5 and CD163+ tumor-associated macrophages better predicts prognosis of clear cell renal cell carcinoma patients.. Cancer Immunol Immunother. 70(10):2925-2935.
Zhan W, Zhang H, Ginn J, Leung A, Liu YJ, Michino M, Toita A, Okamoto R, Wong T-T, Imaeda T et al..  2021.  Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.. Angew Chem Int Ed Engl. 60(17):9279-9283.
Zhan W, Zhang H, Ginn J, Leung A, Liu YJ, Michino M, Toita A, Okamoto R, Wong T-T, Imaeda T et al..  2021.  Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice.. Angew Chem Int Ed Engl. 60(17):9279-9283.
Lee BShi, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMin Sheril, Manimekalai MSony S, Koh VH et al..  2021.  Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.. EMBO Mol Med. 13(1):e13207.
Lee BShi, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMin Sheril, Manimekalai MSony S, Koh VH et al..  2021.  Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.. EMBO Mol Med. 13(1):e13207.
Lee BShi, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMin Sheril, Manimekalai MSony S, Koh VH et al..  2021.  Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.. EMBO Mol Med. 13(1):e13207.
Caniels TG, Bontjer I, van der Straten K, Poniman M, Burger JA, Appelman B, Lavell AHAyesha, Oomen M, Godeke G-J, Valle C et al..  2021.  Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination.. Sci Adv. 7(36):eabj5365.
Caniels TG, Bontjer I, van der Straten K, Poniman M, Burger JA, Appelman B, Lavell AHAyesha, Oomen M, Godeke G-J, Valle C et al..  2021.  Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination.. Sci Adv. 7(36):eabj5365.
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee W-H, Aldon Y, Rantalainen K, Antanasijevic A, Copps J et al..  2021.  Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.. Cell Rep. 35(1):108933.
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee W-H, Aldon Y, Rantalainen K, Antanasijevic A, Copps J et al..  2021.  Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.. Cell Rep. 35(1):108933.
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee W-H, Aldon Y, Rantalainen K, Antanasijevic A, Copps J et al..  2021.  Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.. Cell Rep. 35(1):108933.
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee W-H, Aldon Y, Rantalainen K, Antanasijevic A, Copps J et al..  2021.  Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.. Cell Rep. 35(1):108933.
Yu Z, Song M, Chouchane L, Ma X.  2021.  Functional Genomic Analysis of Breast Cancer Metastasis: Implications for Diagnosis and Therapy.. Cancers (Basel). 13(13)
Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB et al..  2021.  Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.. Cell. 184(17):4579-4592.e24.