Microbiology and Immunology

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2024

Mansfield CR, Quan B, Chirgwin ME, Eduful B, Hughes PF, Neveu G, Sylvester K, Ryan DH, Kafsack BFC, Haystead TAJ et al.. 2024. Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome.. Cell Chem Biol. 31(4):729-742.e13.

Yu Z, Dong X, Song M, Xu A, He Q, Li H, Ouyang W, Chouchane L, Ma X. 2024. Targeting UBR5 inhibits postsurgical breast cancer lung metastases by inducing CDC73 and p53 mediated apoptosis.. Int J Cancer. 154(4):723-737.

Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.. 2024. Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.

Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.. 2024. Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.

Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.. 2024. Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.

Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.. 2024. Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.

Arias AA, Neehus A-L, Ogishi M, Meynier V, Krebs A, Lazarov T, Lee AM, Arango-Franco CA, Yang R, Orrego J et al.. 2024. Tuberculosis in otherwise healthy adults with inherited TNF deficiency.. Nature. 633(8029):417-425.

Hahn WO, K Parks R, Shen M, Ozorowski G, Janes H, Ballweber-Fleming L, Davis ASWoodward, Duplessis C, Tomai M, Dey AK et al.. 2024. Use of 3M-052-AF with Alum adjuvant in HIV trimer vaccine induces human autologous neutralizing antibodies.. J Exp Med. 221(10)

2025

Wu X, Huang S, Gao J, Huang S, Chen L, Zhao Z, Pu R, Ma X, Liu X, He W et al.. 2025. AKR1B10 dictates c-Myc stability to suppress colorectal cancer metastasis via PP2A nitration.. Sci Adv. 11(34):eadv6937.

Du Y, Faz-Lopez B, Kioon MDominique, Cenac C, Pierides M, Lakin KS, Spiera RF, Chaumeil J, Truchetet M-E, Gordon JK et al.. 2025. Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis.. J Exp Med. 222(3)

Du Y, Faz-Lopez B, Kioon MDominique, Cenac C, Pierides M, Lakin KS, Spiera RF, Chaumeil J, Truchetet M-E, Gordon JK et al.. 2025. Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis.. J Exp Med. 222(3)

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

J Vandana J, Zhu J, Giani AMaria, Zhang T, Lacko LA, Leng D, D Taylor L, Lee BN, Han Z, Jiao T et al.. 2025. ChemPerturb-seq screen identifies a small molecule cocktail enhancing human beta cell survival after subcutaneous transplantation.. Cell Stem Cell. 32(8):1299-1307.e8.

Ames L, Allen R, Boshoff HIM, Cleghorn LAT, Engelhart CA, Schnappinger D, Parish T. 2025. Common Biological Properties of Mycobacterium tuberculosis MmpL3 Inhibitors.. ACS Infect Dis.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Molina I, Mansell R, Liang R, Crespo B, Puente M, Franco V, Viera S, Camino I, Saadeddin A, Bellotti P et al.. 2025. The critical role of PSAC channel in malaria parasite survival is driven home by phenotypic screening under relevant nutrient levels.. Cell Chem Biol. 32(6):826-838.e13.

Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al.. 2025. Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.

Davis SH, Mathieson M, Buchanan KI, Dawson A, Smith A, Cocco M, Tamaki FK, Post JM, Baragaña B, Jansen C et al.. 2025. Design and Development of Lysyl tRNA Synthetase Inhibitors, for the Treatment of Tuberculosis.. J Med Chem. 68(15):16459-16482.

Han Y, Leng D, Zhang T, Ge J, Fang Y, Lu T, Dong X, Nair MS, de Silva N, Han Z et al.. 2025. A Human Immuno-Lung Organoid Model to Study Macrophage-Mediated Lung Cell Senescence Upon SARS-CoV-2 Infection.. Adv Sci (Weinh). 12(36):e03932.

Green SR, Harrison JR, Thompson S, Murugesan D, M Libardo DJ, Engelhart CA, Meshanni J, Fletcher D, Scullion P, Edwards D et al.. 2025. Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis.. ACS Infect Dis. 11(3):715-726.

Laurent P, Chaudhary V, Li D, Kioon MDominique, Zhang C, Miller WH, Liao H, Lin G, Nathan CF, Barrat FJ. 2025. The immunoproteasome regulates ILC2 responses by modulating mitochondrial capacity.. Proc Natl Acad Sci U S A. 122(47):e2518190122.

Johnson WC, Alivisatos A, Smith TC, Van N, Soni V, Wallach JB, Clark NA, Fitzgerald TA, Whiteley JJ, Tan S et al.. 2025. Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug action.. Cell Syst. :101348.

Howlader MJ, Ambler WG, Chalasani MLatha S, Rathod A, Seltzer ES, Sim JHyun, Shin J, Schwartz N, Shipman WD, Dasoveanu DC et al.. 2025. Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses.. J Clin Invest. 135(12)