Microbiology and Immunology

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2021
Caniels TG, Bontjer I, van der Straten K, Poniman M, Burger JA, Appelman B, Lavell AHAyesha, Oomen M, Godeke G-J, Valle C et al..  2021.  Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination.. Sci Adv. 7(36):eabj5365.
Derking R, Allen JD, Cottrell CA, Sliepen K, Seabright GE, Lee W-H, Aldon Y, Rantalainen K, Antanasijevic A, Copps J et al..  2021.  Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.. Cell Rep. 35(1):108933.
Wipperman MF, Bhattarai SK, Vorkas CKyriakos, Maringati VSuhas, Taur Y, Mathurin L, McAulay K, Vilbrun SCharles, Francois D, Bean J et al..  2021.  Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis.. Nat Commun. 12(1):1141.
Wipperman MF, Bhattarai SK, Vorkas CKyriakos, Maringati VSuhas, Taur Y, Mathurin L, McAulay K, Vilbrun SCharles, Francois D, Bean J et al..  2021.  Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis.. Nat Commun. 12(1):1141.
Wipperman MF, Bhattarai SK, Vorkas CKyriakos, Maringati VSuhas, Taur Y, Mathurin L, McAulay K, Vilbrun SCharles, Francois D, Bean J et al..  2021.  Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis.. Nat Commun. 12(1):1141.
Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB et al..  2021.  Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis.. Cell. 184(17):4579-4592.e24.
Gouzy A, Healy C, Black KA, Rhee KY, Ehrt S.  2021.  Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity.. Proc Natl Acad Sci U S A. 118(32)
Dingens AS, Pratap P, Malone K, Hilton SK, Ketas T, Cottrell CA, Overbaugh J, Moore JP, Klasse PJ, Ward AB et al..  2021.  High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination.. Elife. 10
Brouwer PJM, Antanasijevic A, de Gast M, Allen JD, Bijl TPL, Yasmeen A, Ravichandran R, Burger JA, Ozorowski G, Torres JL et al..  2021.  Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles.. NPJ Vaccines. 6(1):24.
Brouwer PJM, Antanasijevic A, de Gast M, Allen JD, Bijl TPL, Yasmeen A, Ravichandran R, Burger JA, Ozorowski G, Torres JL et al..  2021.  Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles.. NPJ Vaccines. 6(1):24.
Brouwer PJM, Antanasijevic A, de Gast M, Allen JD, Bijl TPL, Yasmeen A, Ravichandran R, Burger JA, Ozorowski G, Torres JL et al..  2021.  Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles.. NPJ Vaccines. 6(1):24.
Zhang H, Hsu H-C, Kahne SC, Hara R, Zhan W, Jiang X, Burns-Huang K, Ouellette T, Imaeda T, Okamoto R et al..  2021.  Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.. J Med Chem. 64(9):6262-6272.
Black KA, Duan L, Mandyoli L, Selbach BP, Xu W, Ehrt S, Sacchettini JC, Rhee KY.  2021.  Metabolic bifunctionality of Rv0812 couples folate and peptidoglycan biosynthesis in Mycobacterium tuberculosis.. J Exp Med. 218(7)
Bacolod MD, Barany F.  2021.  MGMT Epigenetics: The Influence of Gene Body Methylation and Other Insights Derived from Integrated Methylomic, Transcriptomic, and Chromatin Analyses in Various Cancer Types.. Curr Cancer Drug Targets. 21(4):360-374.
Bacolod MD, Barany F.  2021.  MGMT Epigenetics: The Influence of Gene Body Methylation and Other Insights Derived from Integrated Methylomic, Transcriptomic, and Chromatin Analyses in Various Cancer Types.. Curr Cancer Drug Targets. 21(4):360-374.
Schrader SM, Botella H, Jansen R, Ehrt S, Rhee K, Nathan C, Vaubourgeix J.  2021.  Multiform antimicrobial resistance from a metabolic mutation.. Sci Adv. 7(35)
Beites T, Jansen RS, Wang R, Jinich A, Rhee KY, Schnappinger D, Ehrt S.  2021.  Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection.. Nat Commun. 12(1):6593.
Kioon MDominique, Pierides M, Pannellini T, Lin G, Nathan CF, Barrat FJ.  2021.  Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.. J Immunol. 206(7):1631-1641.
Harnagel A, Quezada LLopez, Park SWoong, Baranowski C, Kieser K, Jiang X, Roberts J, Vaubourgeix J, Yang A, Nelson B et al..  2021.  Nonredundant functions of Mycobacterium tuberculosis chaperones promote survival under stress.. Mol Microbiol. 115(2):272-289.
Saito K, Mishra S, Warrier T, Cicchetti N, Mi J, Weber E, Jiang X, Roberts J, Gouzy A, Kaplan E et al..  2021.  Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected.. Sci Transl Med. 13(621):eabg2612.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J et al..  2021.  Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.. Nat Commun. 12(1):4817.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J et al..  2021.  Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.. Nat Commun. 12(1):4817.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J et al..  2021.  Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.. Nat Commun. 12(1):4817.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J et al..  2021.  Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.. Nat Commun. 12(1):4817.
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J et al..  2021.  Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.. Nat Commun. 12(1):4817.