Microbiology and Immunology

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2014
Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Di Wu T-, Poincloux R et al..  2014.  Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.. PLoS Pathog. 10(2):e1003928.
Gouzy A, Larrouy-Maumus G, Bottai D, Levillain F, Dumas A, Wallach JB, Caire-Brandli I, de Chastellier C, Di Wu T-, Poincloux R et al..  2014.  Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.. PLoS Pathog. 10(2):e1003928.
Danilchanka O, Sun J, Pavlenok M, Maueröder C, Speer A, Siroy A, Marrero J, Trujillo C, Mayhew DL, Doornbos KS et al..  2014.  An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.. Proc Natl Acad Sci U S A. 111(18):6750-5.
Coleman BI, Skillman KM, H Y Jiang R, Childs LM, Altenhofen LM, Ganter M, Leung Y, Goldowitz I, Kafsack BFC, Marti M et al..  2014.  A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion.. Cell Host Microbe. 16(2):177-186.
Kafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA et al..  2014.  A transcriptional switch underlies commitment to sexual development in malaria parasites.. Nature. 507(7491):248-52.
Kafsack BFC, Rovira-Graells N, Clark TG, Bancells C, Crowley VM, Campino SG, Williams AE, Drought LG, Kwiatkowski DP, Baker DA et al..  2014.  A transcriptional switch underlies commitment to sexual development in malaria parasites.. Nature. 507(7491):248-52.
Trujillo C, Blumenthal A, Marrero J, Rhee KY, Schnappinger D, Ehrt S.  2014.  Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection.. mBio. 5(2):e00085.
2013
Kim J-H, O'Brien KM, Sharma R, Boshoff HIM, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC et al..  2013.  A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.. Proc Natl Acad Sci U S A. 110(47):19095-100.
Kim J-H, O'Brien KM, Sharma R, Boshoff HIM, Rehren G, Chakraborty S, Wallach JB, Monteleone M, Wilson DJ, Aldrich CC et al..  2013.  A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.. Proc Natl Acad Sci U S A. 110(47):19095-100.
Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CGK, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M et al..  2013.  Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.. Nature. 504(7478):153-7.
Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CGK, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M et al..  2013.  Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.. Nature. 504(7478):153-7.
Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CGK, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M et al..  2013.  Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.. Nature. 504(7478):153-7.
Rafii S, Kloss CC, Butler JM, Ginsberg M, Gars E, Lis R, Zhan Q, Josipovic P, Ding B-S, Xiang JZ et al..  2013.  Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition.. Blood. 121(5):770-80.
Saenz SA, Siracusa MC, Monticelli LA, Ziegler CGK, Kim BS, Brestoff JR, Peterson LW, E Wherry J, Goldrath AW, Bhandoola A et al..  2013.  IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells.. J Exp Med. 210(9):1823-37.
Saenz SA, Siracusa MC, Monticelli LA, Ziegler CGK, Kim BS, Brestoff JR, Peterson LW, E Wherry J, Goldrath AW, Bhandoola A et al..  2013.  IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells.. J Exp Med. 210(9):1823-37.
Hepworth MR, Monticelli LA, Fung TC, Ziegler CGK, Grunberg S, Sinha R, Mantegazza AR, Ma H-L, Crawford A, Angelosanto JM et al..  2013.  Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.. Nature. 498(7452):113-7.
Bancells C, Deitsch K.  2013.  A molecular switch in the efficiency of translation reinitiation controls expression of var2csa, a gene implicated in pregnancy-associated malaria.. Mol Microbiol. 90(3):472-88.
Lin G, Chidawanyika T, Tsu C, Warrier T, Vaubourgeix J, Blackburn C, Gigstad K, Sintchak M, Dick L, Nathan C.  2013.  N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.. J Am Chem Soc. 135(27):9968-71.
Zhang Y, Lv D, Kim H-J, Kurt RA, Bu W, Li Y, Ma X.  2013.  A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells.. Cell Res. 23(3):394-408.
Small JL, O'Donoghue AJ, Boritsch EC, Tsodikov OV, Knudsen GM, Vandal O, Craik CS, Ehrt S.  2013.  Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.. J Biol Chem. 288(18):12489-99.
Noti M, Wojno EDTait, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA et al..  2013.  Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.. Nat Med. 19(8):1005-13.
Noti M, Wojno EDTait, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA et al..  2013.  Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.. Nat Med. 19(8):1005-13.
Siracusa MC, Saenz SA, Wojno EDTait, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM et al..  2013.  Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.. Immunity. 39(6):1158-70.
Darby CM, Ingólfsson HI, Jiang X, Shen C, Sun M, Zhao N, Burns K, Liu G, Ehrt S, J Warren D et al..  2013.  Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.. PLoS One. 8(7):e68942.
Darby CM, Ingólfsson HI, Jiang X, Shen C, Sun M, Zhao N, Burns K, Liu G, Ehrt S, J Warren D et al..  2013.  Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.. PLoS One. 8(7):e68942.