Submitted by mam2155 on March 24, 2014 - 4:11pm
Title | Pregnancy-associated malaria and the prospects for syndrome-specific antimalaria vaccines. |
Publication Type | Journal Article |
Year of Publication | 2004 |
Authors | Smith JD, Deitsch KW |
Journal | J Exp Med |
Volume | 200 |
Issue | 9 |
Pagination | 1093-7 |
Date Published | 2004 Nov 01 |
ISSN | 0022-1007 |
Keywords | Animals, Chondroitin Sulfates, Erythrocytes, Female, Host-Parasite Interactions, Humans, Malaria Vaccines, Malaria, Falciparum, Placenta, Plasmodium falciparum, Pregnancy, Protozoan Proteins |
Abstract | Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndromes. Here, we discuss the latest advances in the development of a vaccine that specifically targets pregnancy-associated malaria (PAM). |
DOI | 10.1084/jem.20041974 |
Alternate Journal | J Exp Med |
PubMed ID | 15520241 |
PubMed Central ID | PMC2211864 |