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Pregnancy-associated malaria and the prospects for syndrome-specific antimalaria vaccines.

TitlePregnancy-associated malaria and the prospects for syndrome-specific antimalaria vaccines.
Publication TypeJournal Article
Year of Publication2004
AuthorsSmith JD, Deitsch KW
JournalJ Exp Med
Volume200
Issue9
Pagination1093-7
Date Published2004 Nov 01
ISSN0022-1007
KeywordsAnimals, Chondroitin Sulfates, Erythrocytes, Female, Host-Parasite Interactions, Humans, Malaria Vaccines, Malaria, Falciparum, Placenta, Plasmodium falciparum, Pregnancy, Protozoan Proteins
Abstract

Aided by the Plasmodium falciparum genome project, recent discoveries regarding the molecular basis of malaria pathogenesis have led to a better understanding of the interactions between host and parasite. Although vaccines that prevent infection by malaria parasites remain only hopes for the future, there are now more immediate prospects for vaccines that protect against specific disease syndromes. Here, we discuss the latest advances in the development of a vaccine that specifically targets pregnancy-associated malaria (PAM).

DOI10.1084/jem.20041974
Alternate JournalJ Exp Med
PubMed ID15520241
PubMed Central IDPMC2211864

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