Submitted by ljc4002 on August 22, 2025 - 10:41am
| Title | Predictors of Nonseroconversion after SARS-CoV-2 Infection. |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Liu W, Russell RM, Bibollet-Ruche F, Skelly AN, Sherrill-Mix S, Freeman DA, Stoltz R, Lindemuth E, Lee F-H, Sterrett S, Bar KJ, Erdmann N, Gouma S, Hensley SE, Ketas T, Cupo A, Portillo VMCruz, Moore JP, Bieniasz PD, Hatziioannou T, Massey G, Minyard M-B, Saag MS, Davis RS, Shaw GM, Britt WJ, Leal SM, Goepfert P, Hahn BH |
| Journal | Emerg Infect Dis |
| Volume | 27 |
| Issue | 9 |
| Pagination | 2454-2458 |
| Date Published | 2021 Sep |
| ISSN | 1080-6059 |
| Keywords | Antibody Formation, COVID-19, COVID-19 Serological Testing, Humans, Nasopharynx, SARS-CoV-2, Seroconversion |
| Abstract | Not all persons recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop SARS-CoV-2-specific antibodies. We show that nonseroconversion is associated with younger age and higher reverse transcription PCR cycle threshold values and identify SARS-CoV-2 viral loads in the nasopharynx as a major correlate of the systemic antibody response. |
| DOI | 10.3201/eid2709.211042 |
| Alternate Journal | Emerg Infect Dis |
| PubMed ID | 34193339 |
| PubMed Central ID | PMC8386781 |
| Grant List | R37 AI150590 / AI / NIAID NIH HHS / United States T32 GM007170 / GM / NIGMS NIH HHS / United States R01 AI110553 / AI / NIAID NIH HHS / United States U19 AI082630 / AI / NIAID NIH HHS / United States R01 AI050529 / AI / NIAID NIH HHS / United States P01 AI110657 / AI / NIAID NIH HHS / United States P30 AI045008 / AI / NIAID NIH HHS / United States R01 AI036082 / AI / NIAID NIH HHS / United States |