Submitted by mam2155 on March 24, 2014 - 4:15pm
| Title | A popular engagement at the ends. |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Lue NF, Yu EYoung, Lei M |
| Journal | Nat Struct Mol Biol |
| Volume | 20 |
| Issue | 1 |
| Pagination | 10-2 |
| Date Published | 2013 Jan |
| ISSN | 1545-9985 |
| Keywords | Animals, Protein Folding, RNA Interference, RNA, Small Interfering, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Telomerase, Telomere-Binding Proteins |
| Abstract | Three recent studies converged on a specific protein-protein interface between TPP1 and telomerase as being crucial for the regulation of both telomerase recruitment and processivity in mammalian cells. An equivalent interaction appears to exist in budding yeast, making this a nearly universal means of telomerase regulation. |
| DOI | 10.1038/nsmb.2483 |
| Alternate Journal | Nat Struct Mol Biol |
| PubMed ID | 23288360 |
| PubMed Central ID | PMC5560596 |
| Grant List | R01 GM062631 / GM / NIGMS NIH HHS / United States |