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The omentum, a niche for premetastatic ovarian cancer.

TitleThe omentum, a niche for premetastatic ovarian cancer.
Publication TypeJournal Article
Year of Publication2020
AuthorsMa X
JournalJ Exp Med
Volume217
Issue4
Date Published2020 04 06
ISSN1540-9538
KeywordsFemale, Humans, Macrophages, Omentum, Ovarian Neoplasms
Abstract

The work by Etzerodt et al. in this issue of JEM (https://doi.org/10.1084/jem.20191869) identifies a distinct omentum-resident macrophage population of embryonic origin and demonstrates that these cells provide a niche for ovarian cancer metastasis and cancer stemness. This research opens up for many questions and therapeutic prospects.

DOI10.1084/jem.20192312
Alternate JournalJ Exp Med
PubMed ID32103261
PubMed Central IDPMC7144536

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