Nonresolving inflammation redux.

TitleNonresolving inflammation redux.
Publication TypeJournal Article
Year of Publication2022
AuthorsNathan C
JournalImmunity
Volume55
Issue4
Pagination592-605
Date Published2022 Apr 12
ISSN1097-4180
KeywordsCOVID-19, Homeostasis, Humans, Immune System, Inflammation, Nervous System
Abstract

Nonresolving inflammation contributes to many diseases, including COVID-19 in its fatal and long forms. Our understanding of inflammation is rapidly evolving. Like the immune system of which it is a part, inflammation can now be seen as an interactive component of a homeostatic network with the endocrine and nervous systems. This review samples emerging insights regarding inflammatory memory, inflammatory aging, inflammatory cell death, inflammatory DNA, inflammation-regulating cells and metabolites, approaches to resolving or modulating inflammation, and inflammatory inequity.

DOI10.1016/j.immuni.2022.03.016
Alternate JournalImmunity
PubMed ID35417674
PubMed Central IDPMC9003810

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