A mark of silence in malaria parasites.

TitleA mark of silence in malaria parasites.
Publication TypeJournal Article
Year of Publication2009
AuthorsDeitsch KW
JournalCell Host Microbe
Date Published2009 Feb 19
KeywordsAnimals, Antigens, Protozoan, Gene Expression Regulation, Histones, Plasmodium

Gene families in malaria parasites that encode hypervariable surface antigens display mutually exclusive expression that is controlled epigenetically. In this issue, Lopez-Rubio et al. (2009) show that the histone mark H3K9me3 is specifically associated with regulation of expression of these gene families within repressive centers located at the nuclear periphery.

Alternate JournalCell Host Microbe
PubMed ID19218082
Grant ListR01 AI052390 / AI / NIAID NIH HHS / United States

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