Submitted by mam2155 on March 24, 2014 - 4:11pm
Title | Malaria: a peek at the var variorum. |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Chookajorn T, Costanzo MS, Hartl DL, Deitsch KW |
Journal | Trends Parasitol |
Volume | 23 |
Issue | 12 |
Pagination | 563-5 |
Date Published | 2007 Dec |
ISSN | 1471-4922 |
Keywords | Animals, Evolution, Molecular, Genes, Protozoan, Genetic Variation, Humans, Malaria, Falciparum, Plasmodium falciparum |
Abstract | Geneticists encountering the diversity of the malaria parasite's var gene family for the first time often complain that its complexity is a nightmare. A new article by Barry et al. presents the latest and most systematic attempt to date to decipher the var variorum. This important work, combined with other recent articles on var global variation such as that by Kraemer et al., suggests that only the tip of the var diversity iceberg is currently in view. In this article, we discuss these recent results and provide an overview of current understanding of var diversity. |
DOI | 10.1016/j.pt.2007.08.022 |
Alternate Journal | Trends Parasitol |
PubMed ID | 17977793 |