Postdoctoral Associate
Di Qu obtained her Ph.D. in Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai. During her Ph.D. study, she mainly focused on the molecular mechanisms of HIV-1 replication and latency in Dr. Jianhua WANG’s laboratory. She joined Dr. Dirk Schnappinger’s laboratory at Department of Microbiology and Immunology, Weill Cornell Medical in November 2017. At present, she is working on the metabolism of Mycobacterium tuberculosis, specifically biotin synthesis, in attempt to validate new drug targets for tuberculosis treatment.
Publications:
Qu D, Sun WW, Li L, Ma L, Sun L, Jin X, Li T, Hou W, Wang JH. (2019) Long noncoding RNA MALAT1 releases epigenetic silencing of HIV-1 replication by displacing the polycomb repressive complex 2 from binding to the LTR promoter. Nucleic Acids Res. 47(6):3013-3027.
Qu D, Li C, Sang F, Li Q, Jiang ZQ, Xu LR, Guo HJ, Zhang C, Wang JH. (2016) The variances of Sp1 and NF-κB elements correlate with the greater capacity of Chinese HIV-1 B'-LTR for driving gene expression. Sci Rep. 6:34532.
Li C, Kuang WD, Qu D, Wang JH. (2016) Toll-interacting protein inhibits HIV-1 infection and regulates viral latency. Biochem Biophys Res Commun. 475(2):161-8.
Fu-Chun Yang, Wen-Dong Kuang, Chuan Li, Wei-Wei Sun, Di Qu, Jian-Hua Wang. (2015) Toll-Interacting Protein Suppresses HIV-1 Long-Terminal-Repeat-Driven Gene Expression and Silences the Post-Integrational Transcription of Viral Proviral DNA. PLoS One. 10(4):e0125563
