Submitted by alp2017 on April 1, 2016 - 3:31pm
| Title | Dectin-1 Exerts Dual Control in the Gut. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Iliev ID |
| Journal | Cell Host Microbe |
| Volume | 18 |
| Issue | 2 |
| Pagination | 139-41 |
| Date Published | 2015 Aug 12 |
| ISSN | 1934-6069 |
| Abstract | Dectin-1, a β-glucan receptor, contributes to host anti-fungal defense. In this issue of Cell Host & Microbe, Tang et al. (2015) show that suppressing Dectin-1 signaling protects mice from experimental colitis by decreasing anti-microbial peptide production, which allows overgrowth of Lactobacilli and triggers T regulatory cell expansion in the gut. |
| DOI | 10.1016/j.chom.2015.07.010 |
| Alternate Journal | Cell Host Microbe |
| PubMed ID | 26269949 |
| PubMed Central ID | PMC4605567 |
| Grant List | DK098310 / DK / NIDDK NIH HHS / United States K99 DK098310 / DK / NIDDK NIH HHS / United States |