Submitted by jom4013 on December 3, 2020 - 4:17pm
| Title | Closing the feedback loop: how cells "count" telomere-bound proteins. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Lue NF |
| Journal | Mol Cell |
| Volume | 33 |
| Issue | 4 |
| Pagination | 413-4 |
| Date Published | 2009 Feb 27 |
| ISSN | 1097-4164 |
| Keywords | DNA, Fungal, Fungal Proteins, Models, Biological, Telomerase, Telomere, Telomere-Binding Proteins |
| Abstract | Telomere length homeostasis is thought to occur via a "protein-counting" mechanism whereby high numbers of telomere-bound proteins inhibit telomerase activity. In a recent issue of Molecular Cell, Hirano et al. (2009) delineate the molecular interactions that underlie the budding yeast protein-counting machinery. |
| DOI | 10.1016/j.molcel.2009.02.001 |
| Alternate Journal | Mol Cell |
| PubMed ID | 19250901 |