Microbiology and Immunology

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2023

Wong AI, Beites T, Planck KA, Fieweger RA, Eckartt KA, Li S, Poulton NC, VanderVen BC, Rhee KY, Schnappinger D et al.. 2023. Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis.. Elife. 12

Schneider VM, Visone JE, Harris CT, Florini F, Hadjimichael E, Zhang X, Gross MR, Rhee KY, Ben Mamoun C, Kafsack BFC et al.. 2023. The human malaria parasite Plasmodium falciparum can sense environmental changes and respond by antigenic switching.. Proc Natl Acad Sci U S A. 120(17):e2302152120.

Green SR, Wilson C, Eadsforth TC, Punekar AS, Tamaki FK, Wood G, Caldwell N, Forte B, Norcross NR, Kiczun M et al.. 2023. Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.. J Med Chem. 66(22):15380-15408.

Sharma I, Fang J, Lewallen EA, Deitsch KW, McCutchan TF. 2023. Identification of a long noncoding RNA required for temperature induced expression of stage-specific rRNA in malaria parasites.. Gene. 877:147516.

Prabhu M, Yang YJ, Johnston CD, Murphy EA, Ketas TJ, Díaz-Tapia R, Jurkiewicz M, Racine-Brzostek S, Mohammed I, Sukhu AC et al.. 2023. Longitudinal antibody response kinetics following SARS-CoV-2 messenger RNA vaccination in pregnant and nonpregnant persons.. Am J Obstet Gynecol MFM. 5(2):100796.

Bacolod MD, Fisher PB, Barany F. 2023. Multi-CpG linear regression models to accurately predict paclitaxel and docetaxel activity in cancer cell lines.. Adv Cancer Res. 158:233-292.

Wang F, He Q, Zhan W, Yu Z, Finkin-Groner E, Ma X, Lin G, Li H. 2023. Structure of the human UBR5 E3 ubiquitin ligase.. Structure. 31(5):541-552.e4.

Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong T-T, Imaeda T, Hara R et al.. 2023. Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II.. J Med Chem. 66(2):1484-1508.

2022

Heydarchi B, Fong DS, Gao H, Salazar-Quiroz NA, Edwards JM, Gonelli CA, Grimley S, Aktepe TE, Mackenzie C, Wales WJ et al.. 2022. Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody.. Cell Rep Med. 3(5):100635.

Koh E-I, Oluoch PO, Ruecker N, Proulx MK, Soni V, Murphy KC, Papavinasasundaram K, Reames CJ, Trujillo C, Zaveri A et al.. 2022. Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy.. Proc Natl Acad Sci U S A. 119(15):e2201632119.

Zhang X, Florini F, Visone JE, Lionardi I, Gross MR, Patel V, Deitsch KW. 2022. A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites.. Elife. 11

Smith CM, Baker RE, Proulx MK, Mishra BB, Long JE, Park SWoong, Lee H-N, Kiritsy MC, Bellerose MM, Olive AJ et al.. 2022. Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice.. Elife. 11

Gold B, Zhang J, Quezada LLopez, Roberts J, Ling Y, Wood M, Shinwari W, Goullieux L, Roubert C, Fraisse L et al.. 2022. Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions.. ACS Infect Dis. 8(3):557-573.

Gold B, Zhang J, Quezada LLopez, Roberts J, Ling Y, Wood M, Shinwari W, Goullieux L, Roubert C, Fraisse L et al.. 2022. Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions.. ACS Infect Dis. 8(3):557-573.

Lyu M, Suzuki H, Kang L, Gaspal F, Zhou W, Goc J, Zhou L, Zhou J, Zhang W, Shen Z et al.. 2022. ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut.. Nature. 610(7933):744-751.

Lyu M, Suzuki H, Kang L, Gaspal F, Zhou W, Goc J, Zhou L, Zhou J, Zhang W, Shen Z et al.. 2022. ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut.. Nature. 610(7933):744-751.

Ottavi S, Scarry SM, Mosior J, Ling Y, Roberts J, Singh A, Zhang D, Goullieux L, Roubert C, Bacqué E et al.. 2022. In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT by Amidinoureas.. J Med Chem. 65(3):1996-2022.

Green SR, Davis SH, Damerow S, Engelhart CA, Mathieson M, Baragaña B, Robinson DA, Tamjar J, Dawson A, Tamaki FK et al.. 2022. Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs.. Nat Commun. 13(1):5992.

Wilson C, Ray P, Zuccotto F, Hernandez J, Aggarwal A, Mackenzie C, Caldwell N, Taylor M, Huggett M, Mathieson M et al.. 2022. Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.. J Med Chem. 65(1):409-423.

Florini F, Visone JE, Deitsch KW. 2022. Shared Mechanisms for Mutually Exclusive Expression and Antigenic Variation by Protozoan Parasites.. Front Cell Dev Biol. 10:852239.

Govender P, Müller R, Singh K, Reddy V, Eyermann CJ, Fienberg S, Ghorpade SR, Koekemoer L, Myrick A, Schnappinger D et al.. 2022. Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity.. J Med Chem. 65(9):6903-6925.

Zainabadi K, Saito K, Mishra S, Walsh KFrances, Mathurin LDaniel, Vilbrun SCharles, Ocheretina O, Pape JWilliam, Fitzgerald DW, Nathan CF et al.. 2022. Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum.. mBio. 13(6):e0270122.

2021

Ketas TJ, Chaturbhuj D, Portillo VMCruz, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD et al.. 2021. Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.. Pathog Immun. 6(1):116-134.

Ketas TJ, Chaturbhuj D, Portillo VMCruz, Francomano E, Golden E, Chandrasekhar S, Debnath G, Díaz-Tapia R, Yasmeen A, Kramer KD et al.. 2021. Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.. Pathog Immun. 6(1):116-134.

Zainabadi K, Walsh KFrances, Vilbrun SCharles, Mathurin LDaniel, Lee MHee, Saito K, Mishra S, Ocheretina O, Pape JWilliam, Nathan C et al.. 2021. Characterization of Differentially Detectable Mycobacterium tuberculosis in the Sputum of Subjects with Drug-Sensitive or Drug-Resistant Tuberculosis before and after Two Months of Therapy.. Antimicrob Agents Chemother. 65(8):e0060821.