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Found 17 results
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Ketas, Thomas J
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Journal Article
Ingallinella P
,
Bianchi E
,
Ladwa NA
,
Wang Y-J
,
Hrin R
,
Veneziano M
,
Bonelli F
,
Ketas TJ
,
Moore JP
,
Miller MD
et al.
. 2009.
Addition of a cholesterol group to an HIV-1 peptide fusion inhibitor dramatically increases its antiviral potency.
.
Proc Natl Acad Sci U S A. 106(14):5801-6.
Dey AK
,
Cupo A
,
Ozorowski G
,
Sharma VK
,
Behrens A-J
,
Go EP
,
Ketas TJ
,
Yasmeen A
,
Klasse PJ
,
Sayeed E
et al.
. 2018.
cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV-1 envelope glycoprotein vaccine candidate.
.
Biotechnol Bioeng. 115(4):885-899.
Ringe RP
,
Pugach P
,
Cottrell CA
,
LaBranche CC
,
Seabright GE
,
Ketas TJ
,
Ozorowski G
,
Kumar S
,
Schorcht A
,
van Gils MJ
et al.
. 2019.
Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.
.
J Virol. 93(4)
Ketas TJ
,
Schader SM
,
Zurita J
,
Teo E
,
Polonis V
,
Lu M
,
Klasse PJohan
,
Moore JP
. 2007.
Entry inhibitor-based microbicides are active in vitro against HIV-1 isolates from multiple genetic subtypes.
.
Virology. 364(2):431-40.
Ketas TJ
,
Holuigue S
,
Matthews K
,
Moore JP
,
Klasse PJohan
. 2012.
Env-glycoprotein heterogeneity as a source of apparent synergy and enhanced cooperativity in inhibition of HIV-1 infection by neutralizing antibodies and entry inhibitors.
.
Virology. 422(1):22-36.
Banerjee K
,
Andjelic S
,
Klasse PJohan
,
Kang Y
,
Sanders RW
,
Michael E
,
Durso RJ
,
Ketas TJ
,
Olson WC
,
Moore JP
. 2009.
Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo.
.
Virology. 389(1-2):108-21.
Klasse PJ
,
Ketas TJ
,
Cottrell CA
,
Ozorowski G
,
Debnath G
,
Camara D
,
Francomano E
,
Pugach P
,
Ringe RP
,
LaBranche CC
et al.
. 2018.
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
.
PLoS Pathog. 14(2):e1006913.
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Pugach P
,
Ray N
,
Klasse PJohan
,
Ketas TJ
,
Michael E
,
Doms RW
,
Lee B
,
Moore JP
. 2009.
Inefficient entry of vicriviroc-resistant HIV-1 via the inhibitor-CCR5 complex at low cell surface CCR5 densities.
.
Virology. 387(2):296-302.
Pugach P
,
Ketas TJ
,
Michael E
,
Moore JP
. 2008.
Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors.
.
Virology. 377(2):401-7.
Dey AK
,
David KB
,
Ray N
,
Ketas TJ
,
Klasse PJ
,
Doms RW
,
Moore JP
. 2008.
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus.
.
Virology. 372(1):187-200.
Veazey RS
,
Klasse PJohan
,
Schader SM
,
Hu Q
,
Ketas TJ
,
Lu M
,
Marx PA
,
Dufour J
,
Colonno RJ
,
Shattock RJ
et al.
. 2005.
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion.
.
Nature. 438(7064):99-102.
Veazey RS
,
Ketas TJ
,
Dufour J
,
Moroney-Rasmussen T
,
Green LC
,
Klasse PJ
,
Moore JP
. 2010.
Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor.
.
J Infect Dis. 202(5):739-44.
Anastassopoulou CG
,
Ketas TJ
,
Depetris RS
,
Thomas AM
,
Klasse PJohan
,
Moore JP
. 2011.
Resistance of a human immunodeficiency virus type 1 isolate to a small molecule CCR5 inhibitor can involve sequence changes in both gp120 and gp41.
.
Virology. 413(1):47-59.
Anastassopoulou CG
,
Ketas TJ
,
Klasse PJohan
,
Moore JP
. 2009.
Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41.
.
Proc Natl Acad Sci U S A. 106(13):5318-23.
W Horne S
,
Johnson LM
,
Ketas TJ
,
Klasse PJohan
,
Lu M
,
Moore JP
,
Gellman SH
. 2009.
Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers.
.
Proc Natl Acad Sci U S A. 106(35):14751-6.
R Malcolm K
,
Veazey RS
,
Geer L
,
Lowry D
,
Fetherston SM
,
Murphy DJ
,
Boyd P
,
Major I
,
Shattock RJ
,
Klasse PJohan
et al.
. 2012.
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.
.
Antimicrob Agents Chemother. 56(5):2251-8.