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Publications

Found 74 results
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Filters: Author is Schnappinger, Dirk  [Clear All Filters]
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Guo XV, Monteleone M, Klotzsche M, Kamionka A, Hillen W, Braunstein M, Ehrt S, Schnappinger D.  2007.  Silencing Mycobacterium smegmatis by using tetracycline repressors.. J Bacteriol. 189(13):4614-23.
Blumenthal A, Trujillo C, Ehrt S, Schnappinger D.  2010.  Simultaneous analysis of multiple Mycobacterium tuberculosis knockdown mutants in vitro and in vivo.. PLoS One. 5(12):e15667.
Krueger C, Berens C, Schmidt A, Schnappinger D, Hillen W.  2003.  Single-chain Tet transregulators.. Nucleic Acids Res. 31(12):3050-6.
Barry CE, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn JA, Schnappinger D, Wilkinson RJ, Young D.  2009.  The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.. Nat Rev Microbiol. 7(12):845-55.
Subramaniyam S, DeJesus MA, Zaveri A, Smith CM, Baker RE, Ehrt S, Schnappinger D, Sassetti CM, Ioerger TR.  2019.  Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression.. BMC Bioinformatics. 20(1):603.
Vaubourgeix J, Lin G, Dhar N, Chenouard N, Jiang X, Botella H, Lupoli T, Mariani O, Yang G, Ouerfelli O et al..  2015.  Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.. Cell Host Microbe. 17(2):178-90.
Liu F, Dawadi S, Maize KM, Dai R, Park SWoong, Schnappinger D, Finzel BC, Aldrich CC.  2017.  Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.. J Med Chem. 60(13):5507-5520.
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Park SWoong, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC et al..  2015.  Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.. Chem Biol. 22(1):76-86.
Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D et al..  2015.  Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.. J Med Chem. 58(18):7349-7369.
Tiwari D, Park SWoong, Essawy MM, Dawadi S, Mason A, Nandakumar M, Zimmerman M, Mina M, Ho HPin, Engelhart CA et al..  2018.  Targeting protein biotinylation enhances tuberculosis chemotherapy.. Sci Transl Med. 10(438)
Li W, Obregón-Henao A, Wallach JB, E North J, Lee RE, Gonzalez-Juarrero M, Schnappinger D, Jackson M.  2016.  Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.. Antimicrob Agents Chemother. 60(9):5198-207.
Gengenbacher M, Zimmerman MD, Sarathy JP, Kaya F, Wang H, Mina M, Carter C, Hossen MAmir, Su H, Trujillo C et al..  2020.  Tissue Distribution of Doxycycline in Animal Models of Tuberculosis.. Antimicrob Agents Chemother. 64(5)
Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, Monahan IM, Dolganov G, Efron B, Butcher PD, Nathan C et al..  2003.  Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.. J Exp Med. 198(5):693-704.
Trujillo C, Blumenthal A, Marrero J, Rhee KY, Schnappinger D, Ehrt S.  2014.  Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection.. mBio. 5(2):e00085.