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Found 9 results
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Title
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Barry, Clifton E
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2019
Beites T
,
O'Brien K
,
Tiwari D
,
Engelhart CA
,
Walters S
,
Andrews J
,
Yang H-J
,
Sutphen ML
,
Weiner DM
,
Dayao EK
et al.
. 2019.
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.
.
Nat Commun. 10(1):4970.
2018
Oh S
,
Park Y
,
Engelhart CA
,
Wallach JB
,
Schnappinger D
,
Arora K
,
Manikkam M
,
Gac B
,
Wang H
,
Murgolo N
et al.
. 2018.
Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.
.
J Med Chem. 61(22):9952-9965.
2015
Nathan C
,
Barry CE
. 2015.
TB drug development: immunology at the table.
.
Immunol Rev. 264(1):308-18.
2013
Kim J-H
,
O'Brien KM
,
Sharma R
,
Boshoff HIM
,
Rehren G
,
Chakraborty S
,
Wallach JB
,
Monteleone M
,
Wilson DJ
,
Aldrich CC
et al.
. 2013.
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence.
.
Proc Natl Acad Sci U S A. 110(47):19095-100.
2011
Duckworth BP
,
Geders TW
,
Tiwari D
,
Boshoff HI
,
Sibbald PA
,
Barry CE
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2011.
Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis.
.
Chem Biol. 18(11):1432-41.
Park SWoong
,
Klotzsche M
,
Wilson DJ
,
Boshoff HI
,
Eoh H
,
Manjunatha U
,
Blumenthal A
,
Rhee K
,
Barry CE
,
Aldrich CC
et al.
. 2011.
Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.
.
PLoS Pathog. 7(9):e1002264.
Shi C
,
Geders TW
,
Park SWoong
,
Wilson DJ
,
Boshoff HI
,
Abayomi O
,
Barry CE
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2011.
Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis.
.
J Am Chem Soc. 133(45):18194-201.
2009
Barry CE
,
Boshoff HI
,
Dartois V
,
Dick T
,
Ehrt S
,
Flynn JA
,
Schnappinger D
,
Wilkinson RJ
,
Young D
. 2009.
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.
.
Nat Rev Microbiol. 7(12):845-55.
2008
Boshoff HIM
,
Xu X
,
Tahlan K
,
Dowd CS
,
Pethe K
,
Camacho LR
,
Park T-H
,
Yun C-S
,
Schnappinger D
,
Ehrt S
et al.
. 2008.
Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli.
.
J Biol Chem. 283(28):19329-41.