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Found 85 results
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Ehrt, Sabine
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Journal Article
Gandotra S
,
Lebron MB
,
Ehrt S
. 2010.
The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.
.
PLoS Pathog. 6(8):e1001040.
Buter J
,
Cheng T-Y
,
Ghanem M
,
Grootemaat AE
,
Raman S
,
Feng X
,
Plantijn AR
,
Ennis T
,
Wang J
,
Cotton RN
et al.
. 2019.
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
.
Nat Chem Biol. 15(9):889-899.
Lin K
,
O'Brien KM
,
Trujillo C
,
Wang R
,
Wallach JB
,
Schnappinger D
,
Ehrt S
. 2016.
Mycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant Defense.
.
PLoS Pathog. 12(6):e1005675.
Ehrt S
,
Schnappinger D
. 2007.
Mycobacterium tuberculosis virulence: lipids inside and out.
.
Nat Med. 13(3):284-5.
Shi S
,
Nathan C
,
Schnappinger D
,
Drenkow J
,
Fuortes M
,
Block E
,
Ding A
,
Gingeras TR
,
Schoolnik G
,
Akira S
et al.
. 2003.
MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.
.
J Exp Med. 198(7):987-97.
Tan MPing
,
Sequeira P
,
Lin WWei
,
Phong WYee
,
Cliff P
,
Ng SHwee
,
Lee BHeng
,
Camacho L
,
Schnappinger D
,
Ehrt S
et al.
. 2010.
Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses.
.
PLoS One. 5(10):e13356.
Gandotra S
,
Jang S
,
Murray PJ
,
Salgame P
,
Ehrt S
. 2007.
Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.
.
Infect Immun. 75(11):5127-34.
Danilchanka O
,
Sun J
,
Pavlenok M
,
Maueröder C
,
Speer A
,
Siroy A
,
Marrero J
,
Trujillo C
,
Mayhew DL
,
Doornbos KS
et al.
. 2014.
An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.
.
Proc Natl Acad Sci U S A. 111(18):6750-5.
Healy C
,
Gouzy A
,
Ehrt S
. 2020.
Peptidoglycan Hydrolases RipA and Ami1 Are Critical for Replication and Persistence of Mycobacterium tuberculosis in the Host.
.
mBio. 11(2)
Wang R
,
Kreutzfeldt K
,
Botella H
,
Vaubourgeix J
,
Schnappinger D
,
Ehrt S
. 2019.
Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division.
.
Elife. 8
Small JL
,
Park SWoong
,
Kana BD
,
Ioerger TR
,
Sacchettini JC
,
Ehrt S
. 2013.
Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis.
.
mBio. 4(5):e00475-13.
Koo M-S
,
Manca C
,
Yang G
,
O'Brien P
,
Sung N
,
Tsenova L
,
Subbian S
,
Fallows D
,
Muller G
,
Ehrt S
et al.
. 2011.
Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice.
.
PLoS One. 6(2):e17091.
Beites T
,
O'Brien K
,
Tiwari D
,
Engelhart CA
,
Walters S
,
Andrews J
,
Yang H-J
,
Sutphen ML
,
Weiner DM
,
Dayao EK
et al.
. 2019.
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.
.
Nat Commun. 10(1):4970.
K Darwin H
,
Ehrt S
,
Gutierrez-Ramos J-C
,
Weich N
,
Nathan CF
. 2003.
The proteasome of Mycobacterium tuberculosis is required for resistance to nitric oxide.
.
Science. 302(5652):1963-6.
Nathan C
,
Calingasan N
,
Nezezon J
,
Ding A
,
M Lucia S
,
La Perle K
,
Fuortes M
,
Lin M
,
Ehrt S
,
Kwon NSoo
et al.
. 2005.
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase.
.
J Exp Med. 202(9):1163-9.
Schnappinger D
,
Ehrt S
. 2014.
Regulated Expression Systems for Mycobacteria and Their Applications.
.
Microbiol Spectr. 2(1):MGM2-0018-2013.
Schnappinger D
,
Ehrt S
. 2014.
Regulated Expression Systems for Mycobacteria and Their Applications.
.
Microbiol Spectr. 2(1)
Blumenthal A
,
Kobayashi T
,
Pierini LM
,
Banaei N
,
Ernst JD
,
Miyake K
,
Ehrt S
. 2009.
RP105 facilitates macrophage activation by Mycobacterium tuberculosis lipoproteins.
.
Cell Host Microbe. 5(1):35-46.
Bryk R
,
Gold B
,
Venugopal A
,
Singh J
,
Samy R
,
Pupek K
,
Cao H
,
Popescu C
,
Gurney M
,
Hotha S
et al.
. 2008.
Selective killing of nonreplicating mycobacteria.
.
Cell Host Microbe. 3(3):137-45.
Guo XV
,
Monteleone M
,
Klotzsche M
,
Kamionka A
,
Hillen W
,
Braunstein M
,
Ehrt S
,
Schnappinger D
. 2007.
Silencing Mycobacterium smegmatis by using tetracycline repressors.
.
J Bacteriol. 189(13):4614-23.
Blumenthal A
,
Trujillo C
,
Ehrt S
,
Schnappinger D
. 2010.
Simultaneous analysis of multiple Mycobacterium tuberculosis knockdown mutants in vitro and in vivo.
.
PLoS One. 5(12):e15667.
Barry CE
,
Boshoff HI
,
Dartois V
,
Dick T
,
Ehrt S
,
Flynn JA
,
Schnappinger D
,
Wilkinson RJ
,
Young D
. 2009.
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies.
.
Nat Rev Microbiol. 7(12):845-55.
Subramaniyam S
,
DeJesus MA
,
Zaveri A
,
Smith CM
,
Baker RE
,
Ehrt S
,
Schnappinger D
,
Sassetti CM
,
Ioerger TR
. 2019.
Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression.
.
BMC Bioinformatics. 20(1):603.
Biswas T
,
Small J
,
Vandal O
,
Odaira T
,
Deng H
,
Ehrt S
,
Tsodikov OV
. 2010.
Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress.
.
Structure. 18(10):1353-63.
Small JL
,
O'Donoghue AJ
,
Boritsch EC
,
Tsodikov OV
,
Knudsen GM
,
Vandal O
,
Craik CS
,
Ehrt S
. 2013.
Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.
.
J Biol Chem. 288(18):12489-99.
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