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Found 8 results
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Park, Sae Woong
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Journal Article
Rhee KY
,
de Carvalho LPedro Sori
,
Bryk R
,
Ehrt S
,
Marrero J
,
Park SWoong
,
Schnappinger D
,
Venugopal A
,
Nathan C
. 2011.
Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.
.
Trends Microbiol. 19(7):307-14.
Xu W
,
DeJesus MA
,
Rücker N
,
Engelhart CA
,
Wright MG
,
Healy C
,
Lin K
,
Wang R
,
Park SWoong
,
Ioerger TR
et al.
. 2017.
Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis.
.
Antimicrob Agents Chemother. 61(12)
Dai R
,
Geders TW
,
Liu F
,
Park SWoong
,
Schnappinger D
,
Aldrich CC
,
Finzel BC
. 2015.
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.
.
J Med Chem. 58(13):5208-17.
Shi C
,
Geders TW
,
Park SWoong
,
Wilson DJ
,
Boshoff HI
,
Abayomi O
,
Barry CE
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2011.
Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis.
.
J Am Chem Soc. 133(45):18194-201.
Small JL
,
Park SWoong
,
Kana BD
,
Ioerger TR
,
Sacchettini JC
,
Ehrt S
. 2013.
Perturbation of cytochrome c maturation reveals adaptability of the respiratory chain in Mycobacterium tuberculosis.
.
mBio. 4(5):e00475-13.
Liu F
,
Dawadi S
,
Maize KM
,
Dai R
,
Park SWoong
,
Schnappinger D
,
Finzel BC
,
Aldrich CC
. 2017.
Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.
.
J Med Chem. 60(13):5507-5520.
Park SWoong
,
Casalena DE
,
Wilson DJ
,
Dai R
,
Nag PP
,
Liu F
,
Boyce JP
,
Bittker JA
,
Schreiber SL
,
Finzel BC
et al.
. 2015.
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.
.
Chem Biol. 22(1):76-86.
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)