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Ehrt, Sabine
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Puckett S
,
Trujillo C
,
Wang Z
,
Eoh H
,
Ioerger TR
,
Krieger I
,
Sacchettini J
,
Schnappinger D
,
Rhee KY
,
Ehrt S
. 2017.
Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 114(11):E2225-E2232.
H
Shimono N
,
Morici L
,
Casali N
,
Cantrell S
,
Sidders B
,
Ehrt S
,
Riley LW
. 2003.
Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon.
.
Proc Natl Acad Sci U S A. 100(26):15918-23.
I
Wescott HH
,
Zuniga ES
,
Bajpai A
,
Trujillo C
,
Ehrt S
,
Schnappinger D
,
Roberts DM
,
Parish T
. 2018.
Identification of Enolase as the Target of 2-Aminothiazoles in .
.
Front Microbiol. 9:2542.
Zhao N
,
Sun M
,
Burns-Huang K
,
Jiang X
,
Ling Y
,
Darby C
,
Ehrt S
,
Liu G
,
Nathan C
. 2015.
Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis.
.
PLoS One. 10(5):e0126211.
Klotzsche M
,
Ehrt S
,
Schnappinger D
. 2009.
Improved tetracycline repressors for gene silencing in mycobacteria.
.
Nucleic Acids Res. 37(6):1778-88.
Gandotra S
,
Schnappinger D
,
Monteleone M
,
Hillen W
,
Ehrt S
. 2007.
In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.
.
Nat Med. 13(12):1515-20.
Puckett S
,
Trujillo C
,
Eoh H
,
Marrero J
,
Spencer J
,
Jackson M
,
Schnappinger D
,
Rhee K
,
Ehrt S
. 2014.
Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.
.
PLoS Pathog. 10(5):e1004144.
Seimon TA
,
Kim M-J
,
Blumenthal A
,
Koo J
,
Ehrt S
,
Wainwright H
,
Bekker L-G
,
Kaplan G
,
Nathan C
,
Tabas I
et al.
. 2010.
Induction of ER stress in macrophages of tuberculosis granulomas.
.
PLoS One. 5(9):e12772.
Ding A
,
Yu H
,
Yang J
,
Shi S
,
Ehrt S
. 2005.
Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88.
.
Immunology. 116(3):381-9.
Schnappinger D
,
Ehrt S
. 2006.
Introduction: genomic approaches in infectious diseases.
.
Microbes Infect. 8(6):1611-2.
Ehrt S
,
Schnappinger D
. 2003.
Isolation of plasmids from E. coli by alkaline lysis.
.
Methods Mol Biol. 235:75-8.
Ehrt S
,
Schnappinger D
. 2003.
Isolation of plasmids from E. coli by boiling lysis.
.
Methods Mol Biol. 235:79-82.
L
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
Gaur RL
,
Ren K
,
Blumenthal A
,
Bhamidi S
,
González-Nilo FD
,
Gibbs S
,
Jackson M
,
Zare RN
,
Ehrt S
,
Ernst JD
et al.
. 2014.
LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis.
.
PLoS Pathog. 10(9):e1004376.
M
Blumenthal A
,
Nagalingam G
,
Huch JH
,
Walker L
,
Guillemin GJ
,
Smythe GA
,
Ehrt S
,
Britton WJ
,
Saunders BM
. 2012.
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.
.
PLoS One. 7(5):e37314.
Vandal OH
,
Pierini LM
,
Schnappinger D
,
Nathan CF
,
Ehrt S
. 2008.
A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis.
.
Nat Med. 14(8):849-54.
Ehrt S
,
Schnappinger D
,
Rhee KY
. 2018.
Metabolic principles of persistence and pathogenicity in Mycobacterium tuberculosis.
.
Nat Rev Microbiol. 16(8):496-507.
de Carvalho LPedro S
,
Fischer SM
,
Marrero J
,
Nathan C
,
Ehrt S
,
Rhee KY
. 2010.
Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.
.
Chem Biol. 17(10):1122-31.
Ehrt S
,
Rhee K
,
Schnappinger D
. 2015.
Mycobacterial genes essential for the pathogen's survival in the host.
.
Immunol Rev. 264(1):319-26.
Stephanou NC
,
Gao F
,
Bongiorno P
,
Ehrt S
,
Schnappinger D
,
Shuman S
,
Glickman MS
. 2007.
Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks.
.
J Bacteriol. 189(14):5237-46.
Ehrt S
,
Schnappinger D
. 2009.
Mycobacterial survival strategies in the phagosome: defence against host stresses.
.
Cell Microbiol. 11(8):1170-8.
Sakamoto K
,
Kim MJeong
,
Rhoades ER
,
Allavena RE
,
Ehrt S
,
Wainwright HC
,
Russell DG
,
Rohde KH
. 2013.
Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases.
.
Infect Immun. 81(3):764-76.
Darby CM
,
Venugopal A
,
Ehrt S
,
Nathan CF
. 2011.
Mycobacterium tuberculosis gene Rv2136c is dispensable for acid resistance and virulence in mice.
.
Tuberculosis (Edinb). 91(5):343-7.
Ehrt S
,
Rhee K
. 2013.
Mycobacterium tuberculosis metabolism and host interaction: mysteries and paradoxes.
.
Curr Top Microbiol Immunol. 374:163-88.
Botella H
,
Vaubourgeix J
,
Lee MHee
,
Song N
,
Xu W
,
Makinoshima H
,
Glickman MS
,
Ehrt S
. 2017.
Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress.
.
EMBO J. 36(4):536-548.
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