Microbiology and Immunology

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Found 53 results
Author Title Type [ Year(Desc)]
Filters: Author is Lue, Neal F  [Clear All Filters]
2011
Sun J, Yang Y, Wan K, Mao N, Yu T-Y, Lin Y-C, DeZwaan DC, Freeman BC, Lin J-J, Lue NF et al..  2011.  Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase α.. Cell Res. 21(2):258-74.
Belfort M, M Curcio J, Lue NF.  2011.  Telomerase and retrotransposons: reverse transcriptases that shaped genomes.. Proc Natl Acad Sci U S A. 108(51):20304-10.
Yen W-F, Chico L, Lei M, Lue NF.  2011.  Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA.. Proc Natl Acad Sci U S A. 108(51):20370-5.
Lue NF, Hsu M.  2011.  A web of interactions at the ends.. Mol Cell. 42(3):269-71.
2012
Yu EYoung, Sun J, Lei M, Lue NF.  2012.  Analyses of Candida Cdc13 orthologues revealed a novel OB fold dimer arrangement, dimerization-assisted DNA binding, and substantial structural differences between Cdc13 and RPA70.. Mol Cell Biol. 32(1):186-98.
Hsu M, Yu EYoung, Sprušanský O, McEachern MJ, Lue NF.  2012.  Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance.. Eukaryot Cell. 11(7):932-42.
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JHJ, Sung PA, Jasin M et al..  2012.  Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.. PLoS Genet. 8(7):e1002772.
2013
Yu EYoung, Kojic M, Holloman WK, Lue NF.  2013.  Brh2 and Rad51 promote telomere maintenance in Ustilago maydis, a new model system of DNA repair proteins at telomeres.. DNA Repair (Amst). 12(7):472-9.
Lue NF, Chan J.  2013.  Duplication and functional specialization of the telomere-capping protein Cdc13 in Candida species.. J Biol Chem. 288(40):29115-23.
Lue NF, Yu EYoung, Lei M.  2013.  A popular engagement at the ends.. Nat Struct Mol Biol. 20(1):10-2.
Wan B, Yin J, Horvath K, Sarkar J, Chen Y, Wu J, Wan K, Lu J, Gu P, Yu EYoung et al..  2013.  SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres.. Cell Rep. 4(5):861-9.
Lue NF, Zhou R, Chico L, Mao N, Steinberg-Neifach O, Ha T.  2013.  The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with G-Tails, and unfolds higher-order G-tail structures.. PLoS Genet. 9(1):e1003145.
2014
Lue NF, Chan J, Wright WE, Hurwitz J.  2014.  The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch.. Nat Commun. 5:5762.
2015
Steinberg-Neifach O, Wellington K, Vazquez L, Lue NF.  2015.  Combinatorial recognition of a complex telomere repeat sequence by the Candida parapsilosis Cdc13AB heterodimer.. Nucleic Acids Res. 43(4):2164-76.
de Sena-Tomás C, Yu EYoung, Calzada A, Holloman WK, Lue NF, Pérez-Martín J.  2015.  Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres.. Nucleic Acids Res. 43(4):2138-51.
Yu EYoung, Pérez-Martín J, Holloman WK, Lue NF.  2015.  Mre11 and Blm-Dependent Formation of ALT-Like Telomeres in Ku-Deficient Ustilago maydis.. PLoS Genet. 11(10):e1005570.
Steinberg-Neifach O, Lue NF.  2015.  Telomere DNA recognition in Saccharomycotina yeast: potential lessons for the co-evolution of ssDNA and dsDNA-binding proteins and their target sites.. Front Genet. 6:162.
2017
Hsu M, Lue NF.  2017.  Analysis of Yeast Telomerase by Primer Extension Assays.. Methods Mol Biol. 1587:83-93.
Ganduri S, Lue NF.  2017.  STN1-POLA2 interaction provides a basis for primase-pol α stimulation by human STN1.. Nucleic Acids Res. 45(16):9455-9466.
Lue NF, Yu EYoung.  2017.  Telomere recombination pathways: tales of several unhappy marriages.. Curr Genet. 63(3):401-409.
2018
Yu EYoung, Hsu M, Holloman WK, Lue NF.  2018.  Contributions of recombination and repair proteins to telomere maintenance in telomerase-positive and negative Ustilago maydis.. Mol Microbiol. 107(1):81-93.
Lue NF.  2018.  Evolving Linear Chromosomes and Telomeres: A C-Strand-Centric View.. Trends Biochem Sci. 43(5):314-326.
Hsu M, Lue NF.  2018.  The mechanisms of K. lactis Cdc13 in telomere DNA-binding and telomerase regulation.. DNA Repair (Amst). 61:37-45.
Swapna G, Yu EY, Lue NF.  2018.  Single telomere length analysis in Ustilago maydis, a high-resolution tool for examining fungal telomere length distribution and C-strand 5'-end processing.. Microb Cell. 5(9):393-403.
2019
Yu EYoung, Cheung IY, Feng Y, Rabie MO, Roboz GJ, Guzman ML, Cheung N-KV, Lue NF.  2019.  Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma.. Neoplasia. 21(7):689-701.