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Found 59 results
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Nathan, Carl F
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2014
Nathan C
,
Cars O
. 2014.
Antibiotic resistance--problems, progress, and prospects.
.
N Engl J Med. 371(19):1761-3.
2015
Nathan C
. 2015.
Cooperative development of antimicrobials: looking back to look ahead.
.
Nat Rev Microbiol. 13(10):651-7.
Maksymiuk C
,
Balakrishnan A
,
Bryk R
,
Rhee KY
,
Nathan C
. 2015.
E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress.
.
Proc Natl Acad Sci U S A. 112(43):E5834-43.
Zhao N
,
Darby CM
,
Small J
,
Bachovchin DA
,
Jiang X
,
Burns-Huang KE
,
Botella H
,
Ehrt S
,
Boger DL
,
Anderson ED
et al.
. 2015.
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
.
ACS Chem Biol. 10(2):364-71.
Nathan C
,
Barry CE
. 2015.
TB drug development: immunology at the table.
.
Immunol Rev. 264(1):308-18.
Nathan C
. 2015.
What can immunology contribute to the control of the world's leading cause of death from bacterial infection?
Immunol Rev. 264(1):2-5.
2016
Karreci ESula
,
Fan H
,
Uehara M
,
Mihali AB
,
Singh PK
,
Kurdi AT
,
Solhjou Z
,
Riella LV
,
Ghobrial I
,
Laragione T
et al.
. 2016.
Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.
.
Proc Natl Acad Sci U S A. 113(52):E8425-E8432.
Warrier T
,
Kapilashrami K
,
Argyrou A
,
Ioerger TR
,
Little D
,
Murphy KC
,
Nandakumar M
,
Park S
,
Gold B
,
Mi J
et al.
. 2016.
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
.
Proc Natl Acad Sci U S A. 113(31):E4523-30.
Gold B
,
Smith R
,
Nguyen Q
,
Roberts J
,
Ling Y
,
Quezada LLopez
,
Somersan S
,
Warrier T
,
Little D
,
Pingle M
et al.
. 2016.
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
.
J Med Chem. 59(13):6027-44.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Lupoli TJ
,
Fay A
,
Adura C
,
Glickman MS
,
Nathan C
. 2016.
Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.
.
Proc Natl Acad Sci U S A. 113(49):E7947-E7956.
2017
Botella H
,
Yang G
,
Ouerfelli O
,
Ehrt S
,
Nathan CF
,
Vaubourgeix J
. 2017.
Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.
.
mBio. 8(5)
Nathan C
. 2017.
Introduction of Laurie H. Glimcher, MD.
.
J Clin Invest. 127(10):3575.
Nathan C
,
Nussenzweig MC
,
Pulvirenti T
. 2017.
JEM Advisory Editorial Board: Increasing diversity.
.
J Exp Med.
Nathan C
. 2017.
Kunkel Lecture: Fundamental immunodeficiency and its correction.
.
J Exp Med. 214(8):2175-2191.
Nathan C
,
Nussenzweig M
,
Pulvirenti T
. 2017.
The new face of JEM.
.
J Exp Med. 214(12):3467.
Totaro KA
,
Barthelme D
,
Simpson PT
,
Jiang X
,
Lin G
,
Nathan C
,
Sauer RT
,
Sello JK
. 2017.
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
ACS Infect Dis. 3(2):176-181.
Saito K
,
Warrier T
,
Somersan-Karakaya S
,
Kaminski L
,
Mi J
,
Jiang X
,
Park S
,
Shigyo K
,
Gold B
,
Roberts J
et al.
. 2017.
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
.
Proc Natl Acad Sci U S A. 114(24):E4832-E4840.
Santos Rde Luna Al
,
Bai L
,
Singh PK
,
Murakami N
,
Fan H
,
Zhan W
,
Zhu Y
,
Jiang X
,
Zhang K
,
Assker JPierre
et al.
. 2017.
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
.
Nat Commun. 8(1):1692.
Gold B
,
Nathan C
. 2017.
Targeting Phenotypically Tolerant Mycobacterium tuberculosis.
.
Microbiol Spectr. 5(1)
2018
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Yu H
,
Lupoli TJ
,
Kovach A
,
Meng X
,
Zhao G
,
Nathan CF
,
Li H
. 2018.
ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB.
.
Proc Natl Acad Sci U S A. 115(41):E9560-E9569.
McAulay K
,
Saito K
,
Warrier T
,
Walsh KFrances
,
Mathurin LDaniel
,
Royal-Mardi G
,
Lee MHee
,
Ocheretina O
,
Pape JWilliam
,
Fitzgerald DW
et al.
. 2018.
Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.
.
mBio. 9(6)
Mundhra S
,
Bryk R
,
Hawryluk N
,
Zhang T
,
Jiang X
,
Nathan C
. 2018.
Evidence for dispensability of protein kinase R in host control of tuberculosis.
.
Eur J Immunol. 48(4):612-620.
Negri A
,
Javidnia P
,
Mu R
,
Zhang X
,
Vendome J
,
Gold B
,
Roberts J
,
Barman D
,
Ioerger T
,
Sacchettini JC
et al.
. 2018.
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
.
ACS Infect Dis. 4(5):771-787.
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