Microbiology and Immunology

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Zhao N, Sun M, Burns-Huang K, Jiang X, Ling Y, Darby C, Ehrt S, Liu G, Nathan C. 2015. Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis.. PLoS One. 10(5):e0126211.

Wu K, Koo J, Jiang X, Chen R, Cohen SN, Nathan C. 2012. Improved control of tuberculosis and activation of macrophages in mice lacking protein kinase R.. PLoS One. 7(2):e30512.

Seimon TA, Kim M-J, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker L-G, Kaplan G, Nathan C, Tabas I et al.. 2010. Induction of ER stress in macrophages of tuberculosis granulomas.. PLoS One. 5(9):e12772.

Nathan C. 2017. Introduction of Laurie H. Glimcher, MD.. J Clin Invest. 127(10):3575.

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Nathan C, Nussenzweig MC, Pulvirenti T. 2017. JEM Advisory Editorial Board: Increasing diversity.. J Exp Med.

Nathan C. 2013. A journey in science: promise, purpose, privilege.. Mol Med. 19(1):305-13.

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Nathan C. 2017. Kunkel Lecture: Fundamental immunodeficiency and its correction.. J Exp Med. 214(8):2175-2191.

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Bryk R, Lima CD, Erdjument-Bromage H, Tempst P, Nathan C. 2002. Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein.. Science. 295(5557):1073-7.

de Carvalho LPedro S, Fischer SM, Marrero J, Nathan C, Ehrt S, Rhee KY. 2010. Metabolomics of Mycobacterium tuberculosis reveals compartmentalized co-catabolism of carbon substrates.. Chem Biol. 17(10):1122-31.

Shi S, Nathan C, Schnappinger D, Drenkow J, Fuortes M, Block E, Ding A, Gingeras TR, Schoolnik G, Akira S et al.. 2003. MyD88 primes macrophages for full-scale activation by interferon-gamma yet mediates few responses to Mycobacterium tuberculosis.. J Exp Med. 198(7):987-97.

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Lin G, Chidawanyika T, Tsu C, Warrier T, Vaubourgeix J, Blackburn C, Gigstad K, Sintchak M, Dick L, Nathan C. 2013. N,C-Capped dipeptides with selectivity for mycobacterial proteasome over human proteasomes: role of S3 and S1 binding pockets.. J Am Chem Soc. 135(27):9968-71.

Nathan C. 2006. Neutrophils and immunity: challenges and opportunities.. Nat Rev Immunol. 6(3):173-82.

Nathan C, Nussenzweig M, Pulvirenti T. 2017. The new face of JEM.. J Exp Med. 214(12):3467.

de Carvalho LPedro S, Darby CM, Rhee KY, Nathan C. 2011. Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis.. ACS Med Chem Lett. 2(11):849-854.

Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J et al.. 2016. N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 113(31):E4523-30.

Nathan C, Ding A. 2010. Nonresolving inflammation.. Cell. 140(6):871-82.

Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Quezada LLopez, Somersan S, Warrier T, Little D, Pingle M et al.. 2016. Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.. J Med Chem. 59(13):6027-44.

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Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Resto YAlemán, Alsibaee A, Alzualde A et al.. 2016. Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.. PLoS Pathog. 12(7):e1005763.

Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S et al.. 2019. Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.. Science. 363(6426)

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Bryk R, Griffin P, Nathan C. 2000. Peroxynitrite reductase activity of bacterial peroxiredoxins.. Nature. 407(6801):211-5.

Nathan C. 2002. Points of control in inflammation.. Nature. 420(6917):846-52.

Nathan C, Calingasan N, Nezezon J, Ding A, M Lucia S, La Perle K, Fuortes M, Lin M, Ehrt S, Kwon NSoo et al.. 2005. Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase.. J Exp Med. 202(9):1163-9.

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Totaro KA, Barthelme D, Simpson PT, Jiang X, Lin G, Nathan C, Sauer RT, Sello JK. 2017. Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.. ACS Infect Dis. 3(2):176-181.

Lupoli TJ, Fay A, Adura C, Glickman MS, Nathan C. 2016. Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK.. Proc Natl Acad Sci U S A. 113(49):E7947-E7956.

Nathan C. 2020. Resisting antimicrobial resistance.. Nat Rev Microbiol. 18(5):259-260.