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Found 81 results
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2020
Vanheer LN
,
Zhang H
,
Lin G
,
Kafsack BFC
. 2020.
Activity of Epigenetic Inhibitors against Plasmodium falciparum Asexual and Sexual Blood Stages.
.
Antimicrob Agents Chemother. 64(7)
Schrader SM
,
Vaubourgeix J
,
Nathan C
. 2020.
Biology of antimicrobial resistance and approaches to combat it.
.
Sci Transl Med. 12(549)
2019
Ringe RP
,
Pugach P
,
Cottrell CA
,
LaBranche CC
,
Seabright GE
,
Ketas TJ
,
Ozorowski G
,
Kumar S
,
Schorcht A
,
van Gils MJ
et al.
. 2019.
Closing and Opening Holes in the Glycan Shield of HIV-1 Envelope Glycoprotein SOSIP Trimers Can Redirect the Neutralizing Antibody Response to the Newly Unmasked Epitopes.
.
J Virol. 93(4)
McLean KJarrod
,
Straimer J
,
Hopp CS
,
Vega-Rodriguez J
,
Small-Saunders JL
,
Kanatani S
,
Tripathi A
,
Mlambo G
,
Dumoulin PC
,
Harris CT
et al.
. 2019.
Generation of Transmission-Competent Human Malaria Parasites with Chromosomally-Integrated Fluorescent Reporters.
.
Sci Rep. 9(1):13131.
Zhan W
,
Visone J
,
Ouellette T
,
Harris JC
,
Wang R
,
Zhang H
,
Singh PK
,
Ginn J
,
Sukenick G
,
Wong T-T
et al.
. 2019.
Improvement of Asparagine Ethylenediamines as Anti-malarial -Selective Proteasome Inhibitors.
.
J Med Chem. 62(13):6137-6145.
Buter J
,
Cheng T-Y
,
Ghanem M
,
Grootemaat AE
,
Raman S
,
Feng X
,
Plantijn AR
,
Ennis T
,
Wang J
,
Cotton RN
et al.
. 2019.
Mycobacterium tuberculosis releases an antacid that remodels phagosomes.
.
Nat Chem Biol. 15(9):889-899.
Ballinger E
,
Mosior J
,
Hartman T
,
Burns-Huang K
,
Gold B
,
Morris R
,
Goullieux L
,
Blanc I
,
Vaubourgeix J
,
Lagrange S
et al.
. 2019.
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
.
Science. 363(6426)
Wang R
,
Kreutzfeldt K
,
Botella H
,
Vaubourgeix J
,
Schnappinger D
,
Ehrt S
. 2019.
Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division.
.
Elife. 8
Beites T
,
O'Brien K
,
Tiwari D
,
Engelhart CA
,
Walters S
,
Andrews J
,
Yang H-J
,
Sutphen ML
,
Weiner DM
,
Dayao EK
et al.
. 2019.
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development.
.
Nat Commun. 10(1):4970.
Voshtani R
,
Song M
,
Wang H
,
Li X
,
Zhang W
,
Tavallaie MS
,
Yan W
,
Sun J
,
Wei F
,
Ma X
. 2019.
Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment.
.
Cancer Lett. 465:24-35.
2018
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Oh S
,
Park Y
,
Engelhart CA
,
Wallach JB
,
Schnappinger D
,
Arora K
,
Manikkam M
,
Gac B
,
Wang H
,
Murgolo N
et al.
. 2018.
Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.
.
J Med Chem. 61(22):9952-9965.
Klasse PJ
,
Ketas TJ
,
Cottrell CA
,
Ozorowski G
,
Debnath G
,
Camara D
,
Francomano E
,
Pugach P
,
Ringe RP
,
LaBranche CC
et al.
. 2018.
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
.
PLoS Pathog. 14(2):e1006913.
Negri A
,
Javidnia P
,
Mu R
,
Zhang X
,
Vendome J
,
Gold B
,
Roberts J
,
Barman D
,
Ioerger T
,
Sacchettini JC
et al.
. 2018.
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
.
ACS Infect Dis. 4(5):771-787.
Rafiq S
,
Yeku OO
,
Jackson HJ
,
Purdon TJ
,
van Leeuwen DG
,
Drakes DJ
,
Song M
,
Miele MM
,
Li Z
,
Wang P
et al.
. 2018.
Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
.
Nat Biotechnol. 36(9):847-856.
2017
Botella L
,
Vaubourgeix J
,
Livny J
,
Schnappinger D
. 2017.
Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death.
.
Nat Commun. 8:14731.
Botella H
,
Yang G
,
Ouerfelli O
,
Ehrt S
,
Nathan CF
,
Vaubourgeix J
. 2017.
Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis.
.
mBio. 8(5)
Botella H
,
Vaubourgeix J
,
Lee MHee
,
Song N
,
Xu W
,
Makinoshima H
,
Glickman MS
,
Ehrt S
. 2017.
Mycobacterium tuberculosis protease MarP activates a peptidoglycan hydrolase during acid stress.
.
EMBO J. 36(4):536-548.
2016
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
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