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Found 161 results
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2021
Zhang L
,
Jiang X
,
Pfau D
,
Ling Y
,
Nathan CF
. 2021.
Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death.
.
J Exp Med. 218(2)
2020
Schrader SM
,
Vaubourgeix J
,
Nathan C
. 2020.
Biology of antimicrobial resistance and approaches to combat it.
.
Sci Transl Med. 12(549)
Matthews KA
,
Senagbe KM
,
Nötzel C
,
Gonzales CA
,
Tong X
,
Rijo-Ferreira F
,
Bhanu NV
,
Miguel-Blanco C
,
Lafuente-Monasterio MJose
,
Garcia BA
et al.
. 2020.
Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases.
.
ACS Infect Dis. 6(5):1058-1075.
Neveu G
,
Beri D
,
Kafsack BFc
. 2020.
Metabolic regulation of sexual commitment in Plasmodium falciparum.
.
Curr Opin Microbiol. 58:93-98.
Nathan C
. 2020.
Resisting antimicrobial resistance.
.
Nat Rev Microbiol. 18(5):259-260.
2019
Quezada LLopez
,
Silve S
,
Kelinske M
,
Liba A
,
Gonzalez CDiaz
,
Kotev M
,
Goullieux L
,
Sans S
,
Roubert C
,
Lagrange S
et al.
. 2019.
Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
.
mBio. 10(4)
Wu J
,
Mu R
,
Sun M
,
Zhao N
,
Pan M
,
Li H
,
Dong Y
,
Sun Z
,
Bai J
,
Hu M
et al.
. 2019.
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .
.
ACS Infect Dis. 5(7):1087-1104.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
Zimmerman M
,
McDonald SL
,
Ho-Liang H-P
,
Porubsky P
,
Nguyen Q
,
Pharr CW
,
Perkowski AJ
,
Smith R
,
Schoenen FJ
,
Gold BS
et al.
. 2019.
Effect of C-2 substitution on the stability of non-traditional cephalosporins in mouse plasma.
.
J Antibiot (Tokyo). 72(6):469-475.
Early J
,
Ollinger J
,
Darby C
,
Alling T
,
Mullen S
,
Casey A
,
Gold B
,
Ochoada J
,
Wiernicki T
,
Masquelin T
et al.
. 2019.
Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.
.
ACS Infect Dis. 5(2):272-280.
Nathan CF
,
Nussenzweig MC
,
Pulvirenti T
. 2019.
JEM Editorial Board: Expanding on the basis of cancer.
.
J Exp Med. 216(8):1725.
Nathan CF
,
Nussenzweig MC
,
Pulvirenti T
. 2019.
JEM Editorial Board: Expanding on the basis of cancer.
.
J Exp Med. 216(8):1725.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
Freire DMendes
,
Gutierrez C
,
Garza-Garcia A
,
Grabowska AD
,
Sala AJ
,
Ariyachaokun K
,
Panikova T
,
Beckham KSH
,
Colom A
,
Pogenberg V
et al.
. 2019.
An NAD Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
.
Mol Cell. 73(6):1282-1291.e8.
Ballinger E
,
Mosior J
,
Hartman T
,
Burns-Huang K
,
Gold B
,
Morris R
,
Goullieux L
,
Blanc I
,
Vaubourgeix J
,
Lagrange S
et al.
. 2019.
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
.
Science. 363(6426)
Bancells C
,
Llorà-Batlle O
,
Poran A
,
Nötzel C
,
Rovira-Graells N
,
Elemento O
,
Kafsack BFC
,
Cortés A
. 2019.
Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum.
.
Nat Microbiol. 4(1):144-154.
Zhan W
,
Hsu H-C
,
Morgan T
,
Ouellette T
,
Burns-Huang K
,
Hara R
,
Wright AG
,
Imaeda T
,
Okamoto R
,
Sato K
et al.
. 2019.
Selective Phenylimidazole-Based Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
J Med Chem. 62(20):9246-9253.
Mosior J
,
Bourland R
,
Soma S
,
Nathan C
,
Sacchettini J
. 2019.
Structural insights into phosphopantetheinyl hydrolase PptH from Mycobacterium tuberculosis.
.
Protein Sci.
Lee JJin
,
Lee S-K
,
Song N
,
Nathan TO
,
Swarts BM
,
Eum S-Y
,
Ehrt S
,
Cho S-N
,
Eoh H
. 2019.
Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.
.
Nat Commun. 10(1):2928.
2018
Kirkman LA
,
Zhan W
,
Visone J
,
Dziedziech A
,
Singh PK
,
Fan H
,
Tong X
,
Bruzual I
,
Hara R
,
Kawasaki M
et al.
. 2018.
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
.
Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Yu H
,
Lupoli TJ
,
Kovach A
,
Meng X
,
Zhao G
,
Nathan CF
,
Li H
. 2018.
ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB.
.
Proc Natl Acad Sci U S A. 115(41):E9560-E9569.
McAulay K
,
Saito K
,
Warrier T
,
Walsh KFrances
,
Mathurin LDaniel
,
Royal-Mardi G
,
Lee MHee
,
Ocheretina O
,
Pape JWilliam
,
Fitzgerald DW
et al.
. 2018.
Differentially Detectable Mycobacterium tuberculosis Cells in Sputum from Treatment-Naive Subjects in Haiti and Their Proportionate Increase after Initiation of Treatment.
.
mBio. 9(6)
Mundhra S
,
Bryk R
,
Hawryluk N
,
Zhang T
,
Jiang X
,
Nathan C
. 2018.
Evidence for dispensability of protein kinase R in host control of tuberculosis.
.
Eur J Immunol. 48(4):612-620.
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