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Found 65 results
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2021
Zhang L
,
Jiang X
,
Pfau D
,
Ling Y
,
Nathan CF
. 2021.
Type I interferon signaling mediates Mycobacterium tuberculosis-induced macrophage death.
.
J Exp Med. 218(2)
2020
Zaveri A
,
Wang R
,
Botella L
,
Sharma R
,
Zhu L
,
Wallach JB
,
Song N
,
Jansen RS
,
Rhee KY
,
Ehrt S
et al.
. 2020.
Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA-damage response and leads to cell death.
.
Mol Microbiol.
2019
Hu W
,
Zi Z
,
Jin Y
,
Li G
,
Shao K
,
Cai Q
,
Ma X
,
Wei F
. 2019.
CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions.
.
Cancer Immunol Immunother. 68(3):365-377.
Wu J
,
Mu R
,
Sun M
,
Zhao N
,
Pan M
,
Li H
,
Dong Y
,
Sun Z
,
Bai J
,
Hu M
et al.
. 2019.
Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in .
.
ACS Infect Dis. 5(7):1087-1104.
Quezada LLopez
,
Li K
,
McDonald SL
,
Nguyen Q
,
Perkowski AJ
,
Pharr CW
,
Gold B
,
Roberts J
,
McAulay K
,
Saito K
et al.
. 2019.
Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating .
.
ACS Infect Dis. 5(8):1433-1445.
Wang C
,
Li Y
,
Chu C-M
,
Zhang X-M
,
Ma J
,
Huang H
,
Wang Y-N
,
Hong T-Y
,
Zhang J
,
Pan X-W
et al.
. 2019.
Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma.
.
EBioMedicine. 39:255-264.
Wei F
,
Jiang Z
,
Sun H
,
Pu J
,
Sun Y
,
Wang M
,
Tong Q
,
Bi Y
,
Ma X
,
Gao GFu
et al.
. 2019.
Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling.
.
PLoS Pathog. 15(10):e1008062.
Johnson EO
,
LaVerriere E
,
Office E
,
Stanley M
,
Meyer E
,
Kawate T
,
Gomez JE
,
Audette RE
,
Bandyopadhyay N
,
Betancourt N
et al.
. 2019.
Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
.
Nature. 571(7763):72-78.
2018
Mundhra S
,
Bryk R
,
Hawryluk N
,
Zhang T
,
Jiang X
,
Nathan C
. 2018.
Evidence for dispensability of protein kinase R in host control of tuberculosis.
.
Eur J Immunol. 48(4):612-620.
Negri A
,
Javidnia P
,
Mu R
,
Zhang X
,
Vendome J
,
Gold B
,
Roberts J
,
Barman D
,
Ioerger T
,
Sacchettini JC
et al.
. 2018.
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
.
ACS Infect Dis. 4(5):771-787.
Negri A
,
Javidnia P
,
Mu R
,
Zhang X
,
Vendome J
,
Gold B
,
Roberts J
,
Barman D
,
Ioerger T
,
Sacchettini JC
et al.
. 2018.
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
.
ACS Infect Dis. 4(5):771-787.
Rafiq S
,
Yeku OO
,
Jackson HJ
,
Purdon TJ
,
van Leeuwen DG
,
Drakes DJ
,
Song M
,
Miele MM
,
Li Z
,
Wang P
et al.
. 2018.
Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo.
.
Nat Biotechnol. 36(9):847-856.
2017
Ruecker N
,
Jansen R
,
Trujillo C
,
Puckett S
,
Jayachandran P
,
Piroli GG
,
Frizzell N
,
Molina H
,
Rhee KY
,
Ehrt S
. 2017.
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.
.
Cell Chem Biol. 24(3):306-315.
Ruecker N
,
Jansen R
,
Trujillo C
,
Puckett S
,
Jayachandran P
,
Piroli GG
,
Frizzell N
,
Molina H
,
Rhee KY
,
Ehrt S
. 2017.
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.
.
Cell Chem Biol. 24(3):306-315.
Janovitz T
,
Wong S
,
Young NS
,
Oliveira T
,
Falck-Pedersen E
. 2017.
Parvovirus B19 integration into human CD36+ erythroid progenitor cells.
.
Virology. 511:40-48.
Totaro KA
,
Barthelme D
,
Simpson PT
,
Jiang X
,
Lin G
,
Nathan C
,
Sauer RT
,
Sello JK
. 2017.
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
ACS Infect Dis. 3(2):176-181.
Saito K
,
Warrier T
,
Somersan-Karakaya S
,
Kaminski L
,
Mi J
,
Jiang X
,
Park S
,
Shigyo K
,
Gold B
,
Roberts J
et al.
. 2017.
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
.
Proc Natl Acad Sci U S A. 114(24):E4832-E4840.
Saito K
,
Warrier T
,
Somersan-Karakaya S
,
Kaminski L
,
Mi J
,
Jiang X
,
Park S
,
Shigyo K
,
Gold B
,
Roberts J
et al.
. 2017.
Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
.
Proc Natl Acad Sci U S A. 114(24):E4832-E4840.
Santos Rde Luna Al
,
Bai L
,
Singh PK
,
Murakami N
,
Fan H
,
Zhan W
,
Zhu Y
,
Jiang X
,
Zhang K
,
Assker JPierre
et al.
. 2017.
Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes.
.
Nat Commun. 8(1):1692.
2016
Gao M
,
Monian P
,
Pan Q
,
Zhang W
,
Xiang J
,
Jiang X
. 2016.
Ferroptosis is an autophagic cell death process.
.
Cell Res. 26(9):1021-32.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Li W
,
Obregón-Henao A
,
Wallach JB
,
E North J
,
Lee RE
,
Gonzalez-Juarrero M
,
Schnappinger D
,
Jackson M
. 2016.
Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.
.
Antimicrob Agents Chemother. 60(9):5198-207.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
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