Microbiology and Immunology

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Found 161 results
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Journal Article
Cohn EF, Nathan C, Radzioch D, Yu H, Xiang Z, Ding A.  2006.  Abrupt expression of TLR4 in TLR4-deficient macrophages imposes a selective disadvantage: genetic evidence for TLR4-dependent responses to endogenous, nonmicrobial stimuli.. J Immunol. 176(2):1185-94.
Vandal OH, Nathan CF, Ehrt S.  2009.  Acid resistance in Mycobacterium tuberculosis.. J Bacteriol. 191(15):4714-21.
Vandal OH, Roberts JA, Odaira T, Schnappinger D, Nathan CF, Ehrt S.  2009.  Acid-susceptible mutants of Mycobacterium tuberculosis share hypersusceptibility to cell wall and oxidative stress and to the host environment.. J Bacteriol. 191(2):625-31.
de Carvalho LPedro S, Zhao H, Dickinson CE, Arango NM, Lima CD, Fischer SM, Ouerfelli O, Nathan C, Rhee K.  2010.  Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.. Chem Biol. 17(4):323-32.
Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E.  2009.  Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.. J Virol. 83(9):4081-91.
Philpott NJ, Nociari M, Elkon KB, Falck-Pedersen E.  2004.  Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway.. Proc Natl Acad Sci U S A. 101(16):6200-5.
Nathan C.  2007.  Aligning pharmaceutical innovation with medical need.. Nat Med. 13(3):304-8.
MacMicking JD, Nathan C, Hom G, Chartrain N, Fletcher DS, Trumbauer M, Stevens K, Xie QW, Sokol K, Hutchinson N.  1995.  Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase.. Cell. 81(4):641-50.
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J et al..  2005.  Ancestral antibiotic resistance in Mycobacterium tuberculosis.. Proc Natl Acad Sci U S A. 102(34):12200-5.
Nathan C, Cars O.  2014.  Antibiotic resistance--problems, progress, and prospects.. N Engl J Med. 371(19):1761-3.
Nathan C.  2004.  Antibiotics at the crossroads.. Nature. 431(7011):899-902.
Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M et al..  2018.  Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.. Proc Natl Acad Sci U S A. 115(29):E6863-E6870.
Yu H, Lupoli TJ, Kovach A, Meng X, Zhao G, Nathan CF, Li H.  2018.  ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB.. Proc Natl Acad Sci U S A. 115(41):E9560-E9569.
Shimosato T, Kitazawa H, Katoh S, Tohno M, Iliev ID, Nagasawa C, Kimura T, Kawai Y, Saito T.  2005.  Augmentation of T(H)-1 type response by immunoactive AT oligonucleotide from lactic acid bacteria via Toll-like receptor 9 signaling.. Biochem Biophys Res Commun. 326(4):782-7.
Quezada LLopez, Silve S, Kelinske M, Liba A, Gonzalez CDiaz, Kotev M, Goullieux L, Sans S, Roubert C, Lagrange S et al..  2019.  Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.. mBio. 10(4)
Schrader SM, Vaubourgeix J, Nathan C.  2020.  Biology of antimicrobial resistance and approaches to combat it.. Sci Transl Med. 12(549)
Karreci ESula, Fan H, Uehara M, Mihali AB, Singh PK, Kurdi AT, Solhjou Z, Riella LV, Ghobrial I, Laragione T et al..  2016.  Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice.. Proc Natl Acad Sci U S A. 113(52):E8425-E8432.
Nugent CI, Hughes TR, Lue NF, Lundblad V.  1996.  Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance.. Science. 274(5285):249-52.
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Frykman PK, Nordenskjöld A, Kawaguchi A, Hui TT, Granström AL, Cheng Z, Tang J, Underhill DM, Iliev ID, Funari VA et al..  2015.  Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study.. PLoS One. 10(4):e0124172.
Niu H, Xia J, Lue NF.  2000.  Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex.. Mol Cell Biol. 20(18):6806-15.
Xie QW, Cho HJ, Calaycay J, Mumford RA, Swiderek KM, Lee TD, Ding A, Troso T, Nathan C.  1992.  Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.. Science. 256(5054):225-8.
Niederweis M, Ehrt S, Heinz C, Klöcker U, Karosi S, Swiderek KM, Riley LW, Benz R.  1999.  Cloning of the mspA gene encoding a porin from Mycobacterium smegmatis.. Mol Microbiol. 33(5):933-45.
Zeng Z-S, Weiser MR, Kuntz E, Chen C-T, Khan SA, Forslund A, Nash GM, Gimbel M, Yamaguchi Y, Culliford AT et al..  2008.  c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases.. Cancer Lett. 265(2):258-69.