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Journal Article
Darby CM
,
Ingólfsson HI
,
Jiang X
,
Shen C
,
Sun M
,
Zhao N
,
Burns K
,
Liu G
,
Ehrt S
,
J Warren D
et al.
. 2013.
Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.
.
PLoS One. 8(7):e68942.
Venugopal A
,
Bryk R
,
Shi S
,
Rhee K
,
Rath P
,
Schnappinger D
,
Ehrt S
,
Nathan C
. 2011.
Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.
.
Cell Host Microbe. 9(1):21-31.
Peng Y
,
Falck-Pedersen E
,
Elkon KB
. 2001.
Variation in adenovirus transgene expression between BALB/c and C57BL/6 mice is associated with differences in interleukin-12 and gamma interferon production and NK cell activation.
.
J Virol. 75(10):4540-50.
Ehrt S
,
Hillen W
. 1994.
UDP-N-acetylglucosamine 1-carboxyvinyl-transferase from Acinetobacter calcoaceticus.
.
FEMS Microbiol Lett. 117(2):137-42.
Geissdörfer W
,
Frosch SC
,
Haspel G
,
Ehrt S
,
Hillen W
. 1995.
Two genes encoding proteins with similarities to rubredoxin and rubredoxin reductase are required for conversion of dodecane to lauric acid in Acinetobacter calcoaceticus ADP1.
.
Microbiology (Reading). 141 ( Pt 6):1425-32.
Ganapathy U
,
Marrero J
,
Calhoun S
,
Eoh H
,
de Carvalho LPedro Sori
,
Rhee K
,
Ehrt S
. 2015.
Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.
.
Nat Commun. 6:7912.
Ganapathy U
,
Marrero J
,
Calhoun S
,
Eoh H
,
de Carvalho LPedro Sori
,
Rhee K
,
Ehrt S
. 2015.
Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis.
.
Nat Commun. 6:7912.
Elkon KB
,
Liu CC
,
Gall JG
,
Trevejo J
,
Marino MW
,
Abrahamsen KA
,
Song X
,
Zhou JL
,
Old LJ
,
Crystal RG
et al.
. 1997.
Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors.
.
Proc Natl Acad Sci U S A. 94(18):9814-9.
Trujillo C
,
Blumenthal A
,
Marrero J
,
Rhee KY
,
Schnappinger D
,
Ehrt S
. 2014.
Triosephosphate isomerase is dispensable in vitro yet essential for Mycobacterium tuberculosis to establish infection.
.
mBio. 5(2):e00085.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
Lee JJin
,
Lee S-K
,
Song N
,
Nathan TO
,
Swarts BM
,
Eum S-Y
,
Ehrt S
,
Cho S-N
,
Eoh H
. 2019.
Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.
.
Nat Commun. 10(1):2928.
Lee JJin
,
Lee S-K
,
Song N
,
Nathan TO
,
Swarts BM
,
Eum S-Y
,
Ehrt S
,
Cho S-N
,
Eoh H
. 2019.
Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.
.
Nat Commun. 10(1):2928.
Lee JJin
,
Lee S-K
,
Song N
,
Nathan TO
,
Swarts BM
,
Eum S-Y
,
Ehrt S
,
Cho S-N
,
Eoh H
. 2019.
Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.
.
Nat Commun. 10(1):2928.
Kim S
,
Elkon KB
,
Ma X
. 2004.
Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells.
.
Immunity. 21(5):643-53.
Schnappinger D
,
Ehrt S
,
Voskuil MI
,
Liu Y
,
Mangan JA
,
Monahan IM
,
Dolganov G
,
Efron B
,
Butcher PD
,
Nathan C
et al.
. 2003.
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.
.
J Exp Med. 198(5):693-704.
Schnappinger D
,
Ehrt S
,
Voskuil MI
,
Liu Y
,
Mangan JA
,
Monahan IM
,
Dolganov G
,
Efron B
,
Butcher PD
,
Nathan C
et al.
. 2003.
Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment.
.
J Exp Med. 198(5):693-704.
Trevejo JM
,
Marino MW
,
Philpott N
,
Josien R
,
Richards EC
,
Elkon KB
,
Falck-Pedersen E
. 2001.
TNF-alpha -dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection.
.
Proc Natl Acad Sci U S A. 98(21):12162-7.
Gengenbacher M
,
Zimmerman MD
,
Sarathy JP
,
Kaya F
,
Wang H
,
Mina M
,
Carter C
,
Hossen MAmir
,
Su H
,
Trujillo C
et al.
. 2020.
Tissue Distribution of Doxycycline in Animal Models of Tuberculosis.
.
Antimicrob Agents Chemother. 64(5)
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)
Tiwari D
,
Park SWoong
,
Essawy MM
,
Dawadi S
,
Mason A
,
Nandakumar M
,
Zimmerman M
,
Mina M
,
Ho HPin
,
Engelhart CA
et al.
. 2018.
Targeting protein biotinylation enhances tuberculosis chemotherapy.
.
Sci Transl Med. 10(438)
Melchers M
,
Bontjer I
,
Tong T
,
P Y Chung N
,
Klasse PJohan
,
Eggink D
,
Montefiori DC
,
Gentile M
,
Cerutti A
,
Olson WC
et al.
. 2012.
Targeting HIV-1 envelope glycoprotein trimers to B cells by using APRIL improves antibody responses.
.
J Virol. 86(5):2488-500.
Zhao N
,
Darby CM
,
Small J
,
Bachovchin DA
,
Jiang X
,
Burns-Huang KE
,
Botella H
,
Ehrt S
,
Boger DL
,
Anderson ED
et al.
. 2015.
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
.
ACS Chem Biol. 10(2):364-71.
Zhao N
,
Darby CM
,
Small J
,
Bachovchin DA
,
Jiang X
,
Burns-Huang KE
,
Botella H
,
Ehrt S
,
Boger DL
,
Anderson ED
et al.
. 2015.
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
.
ACS Chem Biol. 10(2):364-71.
Small JL
,
O'Donoghue AJ
,
Boritsch EC
,
Tsodikov OV
,
Knudsen GM
,
Vandal O
,
Craik CS
,
Ehrt S
. 2013.
Substrate specificity of MarP, a periplasmic protease required for resistance to acid and oxidative stress in Mycobacterium tuberculosis.
.
J Biol Chem. 288(18):12489-99.
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