Microbiology and Immunology

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Found 205 results
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2012
Iliev ID, Funari VA, Taylor KD, Nguyen Q, Reyes CN, Strom SP, Brown J, Becker CA, Fleshner PR, Dubinsky M et al..  2012.  Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis.. Science. 336(6086):1314-7.
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JHJ, Sung PA, Jasin M et al..  2012.  Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.. PLoS Genet. 8(7):e1002772.
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JHJ, Sung PA, Jasin M et al..  2012.  Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.. PLoS Genet. 8(7):e1002772.
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JHJ, Sung PA, Jasin M et al..  2012.  Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.. PLoS Genet. 8(7):e1002772.
R Malcolm K, Veazey RS, Geer L, Lowry D, Fetherston SM, Murphy DJ, Boyd P, Major I, Shattock RJ, Klasse PJohan et al..  2012.  Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques.. Antimicrob Agents Chemother. 56(5):2251-8.
2011
Rhee KY, de Carvalho LPedro Sori, Bryk R, Ehrt S, Marrero J, Park SWoong, Schnappinger D, Venugopal A, Nathan C.  2011.  Central carbon metabolism in Mycobacterium tuberculosis: an unexpected frontier.. Trends Microbiol. 19(7):307-14.
Wei J-R, Krishnamoorthy V, Murphy K, Kim J-H, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ.  2011.  Depletion of antibiotic targets has widely varying effects on growth.. Proc Natl Acad Sci U S A. 108(10):4176-81.
Wei J-R, Krishnamoorthy V, Murphy K, Kim J-H, Schnappinger D, Alber T, Sassetti CM, Rhee KY, Rubin EJ.  2011.  Depletion of antibiotic targets has widely varying effects on growth.. Proc Natl Acad Sci U S A. 108(10):4176-81.
Park SWoong, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC et al..  2011.  Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.. PLoS Pathog. 7(9):e1002264.
Santangelo Mde la Paz, Gest PM, Guerin ME, Coinçon M, Pham H, Ryan G, Puckett SE, Spencer JS, Gonzalez-Juarrero M, Daher R et al..  2011.  Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.. J Biol Chem. 286(46):40219-31.
Williams KJ, Boshoff HI, Krishnan N, Gonzales J, Schnappinger D, Robertson BD.  2011.  The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo.. Tuberculosis (Edinb). 91(6):549-55.
de Carvalho LPedro S, Darby CM, Rhee KY, Nathan C.  2011.  Nitazoxanide Disrupts Membrane Potential and Intrabacterial pH Homeostasis of Mycobacterium tuberculosis.. ACS Med Chem Lett. 2(11):849-854.
Pejchal R, Doores KJ, Walker LM, Khayat R, Huang P-S, Wang S-K, Stanfield RL, Julien J-P, Ramos A, Crispin M et al..  2011.  A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield.. Science. 334(6059):1097-103.
Kim J-H, Wei J-R, Wallach JB, Robbins RS, Rubin EJ, Schnappinger D.  2011.  Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase.. Nucleic Acids Res. 39(6):2210-20.
Kim J-H, Wei J-R, Wallach JB, Robbins RS, Rubin EJ, Schnappinger D.  2011.  Protein inactivation in mycobacteria by controlled proteolysis and its application to deplete the beta subunit of RNA polymerase.. Nucleic Acids Res. 39(6):2210-20.
Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C.  2011.  Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.. Cell Host Microbe. 9(1):21-31.
Venugopal A, Bryk R, Shi S, Rhee K, Rath P, Schnappinger D, Ehrt S, Nathan C.  2011.  Virulence of Mycobacterium tuberculosis depends on lipoamide dehydrogenase, a member of three multienzyme complexes.. Cell Host Microbe. 9(1):21-31.
2010
de Carvalho LPedro S, Zhao H, Dickinson CE, Arango NM, Lima CD, Fischer SM, Ouerfelli O, Nathan C, Rhee K.  2010.  Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase.. Chem Biol. 17(4):323-32.
Kaner RJ, Santiago F, Rahaghi F, Michaels E, Moore JP, Crystal RG.  2010.  Adenovirus vectors block human immunodeficiency virus-1 replication in human alveolar macrophages by inhibition of the long terminal repeat.. Am J Respir Cell Mol Biol. 43(2):234-42.
Beaulieu AM, Rath P, Imhof M, Siddall ME, Roberts J, Schnappinger D, Nathan CF.  2010.  Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.. PLoS One. 5(12):e15120.
Beaulieu AM, Rath P, Imhof M, Siddall ME, Roberts J, Schnappinger D, Nathan CF.  2010.  Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.. PLoS One. 5(12):e15120.
Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S.  2010.  Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection.. Proc Natl Acad Sci U S A. 107(21):9819-24.
Matteoli G, Mazzini E, Iliev ID, Mileti E, Fallarino F, Puccetti P, Chieppa M, Rescigno M.  2010.  Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.. Gut. 59(5):595-604.
Murakami M, Francavilla C, Torselli I, Corada M, Maddaluno L, Sica A, Matteoli G, Iliev ID, Mantovani A, Rescigno M et al..  2010.  Inactivation of junctional adhesion molecule-A enhances antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration.. Cancer Res. 70(5):1759-65.
Seimon TA, Kim M-J, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker L-G, Kaplan G, Nathan C, Tabas I et al..  2010.  Induction of ER stress in macrophages of tuberculosis granulomas.. PLoS One. 5(9):e12772.