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2016
Gold B
,
Smith R
,
Nguyen Q
,
Roberts J
,
Ling Y
,
Quezada LLopez
,
Somersan S
,
Warrier T
,
Little D
,
Pingle M
et al.
. 2016.
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
.
J Med Chem. 59(13):6027-44.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
2015
Dai R
,
Geders TW
,
Liu F
,
Park SWoong
,
Schnappinger D
,
Aldrich CC
,
Finzel BC
. 2015.
Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.
.
J Med Chem. 58(13):5208-17.
de Sena-Tomás C
,
Yu EYoung
,
Calzada A
,
Holloman WK
,
Lue NF
,
Pérez-Martín J
. 2015.
Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres.
.
Nucleic Acids Res. 43(4):2138-51.
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Ringe RP
,
Yasmeen A
,
Ozorowski G
,
Go EP
,
Pritchard LK
,
Guttman M
,
Ketas TA
,
Cottrell CA
,
Wilson IA
,
Sanders RW
et al.
. 2015.
Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.
.
J Virol. 89(23):12189-210.
Yu EYoung
,
Pérez-Martín J
,
Holloman WK
,
Lue NF
. 2015.
Mre11 and Blm-Dependent Formation of ALT-Like Telomeres in Ku-Deficient Ustilago maydis.
.
PLoS Genet. 11(10):e1005570.
Park SWoong
,
Casalena DE
,
Wilson DJ
,
Dai R
,
Nag PP
,
Liu F
,
Boyce JP
,
Bittker JA
,
Schreiber SL
,
Finzel BC
et al.
. 2015.
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.
.
Chem Biol. 22(1):76-86.
Bockman MR
,
Kalinda AS
,
Petrelli R
,
De la Mora-Rey T
,
Tiwari D
,
Liu F
,
Dawadi S
,
Nandakumar M
,
Rhee KY
,
Schnappinger D
et al.
. 2015.
Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.
.
J Med Chem. 58(18):7349-7369.
2014
Sinha A
,
Hughes KR
,
Modrzynska KK
,
Otto TD
,
Pfander C
,
Dickens NJ
,
Religa AA
,
Bushell E
,
Graham AL
,
Cameron R
et al.
. 2014.
A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.
.
Nature. 507(7491):253-257.
Sander AF
,
Lavstsen T
,
Rask TS
,
Lisby M
,
Salanti A
,
Fordyce SL
,
Jespersen JS
,
Carter R
,
Deitsch K
,
Theander TG
et al.
. 2014.
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.
.
Nucleic Acids Res. 42(4):2270-81.
Puckett S
,
Trujillo C
,
Eoh H
,
Marrero J
,
Spencer J
,
Jackson M
,
Schnappinger D
,
Rhee K
,
Ehrt S
. 2014.
Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.
.
PLoS Pathog. 10(5):e1004144.
Gouzy A
,
Larrouy-Maumus G
,
Bottai D
,
Levillain F
,
Dumas A
,
Wallach JB
,
Caire-Brandli I
,
de Chastellier C
,
Di Wu T-
,
Poincloux R
et al.
. 2014.
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.
.
PLoS Pathog. 10(2):e1003928.
Gouzy A
,
Larrouy-Maumus G
,
Bottai D
,
Levillain F
,
Dumas A
,
Wallach JB
,
Caire-Brandli I
,
de Chastellier C
,
Di Wu T-
,
Poincloux R
et al.
. 2014.
Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection.
.
PLoS Pathog. 10(2):e1003928.
Danilchanka O
,
Sun J
,
Pavlenok M
,
Maueröder C
,
Speer A
,
Siroy A
,
Marrero J
,
Trujillo C
,
Mayhew DL
,
Doornbos KS
et al.
. 2014.
An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.
.
Proc Natl Acad Sci U S A. 111(18):6750-5.
Raju RM
,
Jedrychowski MP
,
Wei J-R
,
Pinkham JT
,
Park AS
,
O'Brien K
,
Rehren G
,
Schnappinger D
,
Gygi SP
,
Rubin EJ
. 2014.
Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.
.
PLoS Pathog. 10(3):e1003994.
Raju RM
,
Jedrychowski MP
,
Wei J-R
,
Pinkham JT
,
Park AS
,
O'Brien K
,
Rehren G
,
Schnappinger D
,
Gygi SP
,
Rubin EJ
. 2014.
Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.
.
PLoS Pathog. 10(3):e1003994.
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