Microbiology and Immunology

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Journal Article
Gold B, Deng H, Bryk R, Vargas D, Eliezer D, Roberts J, Jiang X, Nathan C.  2008.  Identification of a copper-binding metallothionein in pathogenic mycobacteria.. Nat Chem Biol. 4(10):609-16.
Early J, Ollinger J, Darby C, Alling T, Mullen S, Casey A, Gold B, Ochoada J, Wiernicki T, Masquelin T et al..  2019.  Identification of Compounds with pH-Dependent Bactericidal Activity against Mycobacterium tuberculosis.. ACS Infect Dis. 5(2):272-280.
Wescott HH, Zuniga ES, Bajpai A, Trujillo C, Ehrt S, Schnappinger D, Roberts DM, Parish T.  2018.  Identification of Enolase as the Target of 2-Aminothiazoles in .. Front Microbiol. 9:2542.
Zhao N, Sun M, Burns-Huang K, Jiang X, Ling Y, Darby C, Ehrt S, Liu G, Nathan C.  2015.  Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis.. PLoS One. 10(5):e0126211.
Kass-Eisler A, Falck-Pedersen E, Elfenbein DH, Alvira M, Buttrick PM, Leinwand LA.  1994.  The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer.. Gene Ther. 1(6):395-402.
Klotzsche M, Ehrt S, Schnappinger D.  2009.  Improved tetracycline repressors for gene silencing in mycobacteria.. Nucleic Acids Res. 37(6):1778-88.
Gandotra S, Schnappinger D, Monteleone M, Hillen W, Ehrt S.  2007.  In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice.. Nat Med. 13(12):1515-20.
Puckett S, Trujillo C, Eoh H, Marrero J, Spencer J, Jackson M, Schnappinger D, Rhee K, Ehrt S.  2014.  Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.. PLoS Pathog. 10(5):e1004144.
Puckett S, Trujillo C, Eoh H, Marrero J, Spencer J, Jackson M, Schnappinger D, Rhee K, Ehrt S.  2014.  Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.. PLoS Pathog. 10(5):e1004144.
Seimon TA, Kim M-J, Blumenthal A, Koo J, Ehrt S, Wainwright H, Bekker L-G, Kaplan G, Nathan C, Tabas I et al..  2010.  Induction of ER stress in macrophages of tuberculosis granulomas.. PLoS One. 5(9):e12772.
Ding A, Yu H, Yang J, Shi S, Ehrt S.  2005.  Induction of macrophage-derived SLPI by Mycobacterium tuberculosis depends on TLR2 but not MyD88.. Immunology. 116(3):381-9.
Peng Y, Trevejo J, Zhou J, Marino MW, Crystal RG, Falck-Pedersen E, Elkon KB.  1999.  Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung.. J Virol. 73(6):5098-109.
Hepworth MR, Monticelli LA, Fung TC, Ziegler CGK, Grunberg S, Sinha R, Mantegazza AR, Ma H-L, Crawford A, Angelosanto JM et al..  2013.  Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.. Nature. 498(7452):113-7.
Hepworth MR, Monticelli LA, Fung TC, Ziegler CGK, Grunberg S, Sinha R, Mantegazza AR, Ma H-L, Crawford A, Angelosanto JM et al..  2013.  Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria.. Nature. 498(7452):113-7.
Schnappinger D, Ehrt S.  2006.  Introduction: genomic approaches in infectious diseases.. Microbes Infect. 8(6):1611-2.
Kim SJun, Gershov D, Ma X, Brot N, Elkon KB.  2002.  I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation.. J Exp Med. 196(5):655-65.
Zeng H, Guo M, Zhou T, Tan L, Chong CNok, Zhang T, Dong X, Xiang JZhaoying, Yu AS, Yue L et al..  2016.  An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery.. Cell Stem Cell. 19(3):326-40.
Ehrt S, Schnappinger D.  2003.  Isolation of plasmids from E. coli by alkaline lysis.. Methods Mol Biol. 235:75-8.
Ehrt S, Schnappinger D.  2003.  Isolation of plasmids from E. coli by boiling lysis.. Methods Mol Biol. 235:79-82.
Eggink D, Melchers M, Wuhrer M, van Montfort T, Dey AK, Naaijkens BA, David KB, Le Douce V, Deelder AM, Kang K et al..  2010.  Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function.. Virology. 401(2):236-47.
Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N et al..  2019.  Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.. Nature. 571(7763):72-78.
Gaur RL, Ren K, Blumenthal A, Bhamidi S, González-Nilo FD, Gibbs S, Jackson M, Zare RN, Ehrt S, Ernst JD et al..  2014.  LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis.. PLoS Pathog. 10(9):e1004376.
Gaur RL, Ren K, Blumenthal A, Bhamidi S, González-Nilo FD, Gibbs S, Jackson M, Zare RN, Ehrt S, Ernst JD et al..  2014.  LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis.. PLoS Pathog. 10(9):e1004376.
Blumenthal A, Nagalingam G, Huch JH, Walker L, Guillemin GJ, Smythe GA, Ehrt S, Britton WJ, Saunders BM.  2012.  M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.. PLoS One. 7(5):e37314.
Dzikowski R, Li F, Amulic B, Eisberg A, Frank M, Patel S, Wellems TE, Deitsch KW.  2007.  Mechanisms underlying mutually exclusive expression of virulence genes by malaria parasites.. EMBO Rep. 8(10):959-65.