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Found 65 results
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2013
Janovitz T
,
Klein IA
,
Oliveira T
,
Mukherjee P
,
Nussenzweig MC
,
Sadelain M
,
Falck-Pedersen E
. 2013.
High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration.
.
J Virol. 87(15):8559-68.
Alenghat T
,
Osborne LC
,
Saenz SA
,
Kobuley D
,
Ziegler CGK
,
Mullican SE
,
Choi I
,
Grunberg S
,
Sinha R
,
Wynosky-Dolfi M
et al.
. 2013.
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.
.
Nature. 504(7478):153-7.
Rafii S
,
Kloss CC
,
Butler JM
,
Ginsberg M
,
Gars E
,
Lis R
,
Zhan Q
,
Josipovic P
,
Ding B-S
,
Xiang JZ
et al.
. 2013.
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition.
.
Blood. 121(5):770-80.
Rafii S
,
Kloss CC
,
Butler JM
,
Ginsberg M
,
Gars E
,
Lis R
,
Zhan Q
,
Josipovic P
,
Ding B-S
,
Xiang JZ
et al.
. 2013.
Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition.
.
Blood. 121(5):770-80.
Darby CM
,
Ingólfsson HI
,
Jiang X
,
Shen C
,
Sun M
,
Zhao N
,
Burns K
,
Liu G
,
Ehrt S
,
J Warren D
et al.
. 2013.
Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.
.
PLoS One. 8(7):e68942.
2014
Janovitz T
,
Sadelain M
,
Falck-Pedersen E
. 2014.
Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints.
.
Virol J. 11:15.
Sander AF
,
Lavstsen T
,
Rask TS
,
Lisby M
,
Salanti A
,
Fordyce SL
,
Jespersen JS
,
Carter R
,
Deitsch K
,
Theander TG
et al.
. 2014.
DNA secondary structures are associated with recombination in major Plasmodium falciparum variable surface antigen gene families.
.
Nucleic Acids Res. 42(4):2270-81.
Janovitz T
,
Oliveira T
,
Sadelain M
,
Falck-Pedersen E
. 2014.
Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing.
.
J Virol. 88(5):2481-8.
Puckett S
,
Trujillo C
,
Eoh H
,
Marrero J
,
Spencer J
,
Jackson M
,
Schnappinger D
,
Rhee K
,
Ehrt S
. 2014.
Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.
.
PLoS Pathog. 10(5):e1004144.
Gaur RL
,
Ren K
,
Blumenthal A
,
Bhamidi S
,
González-Nilo FD
,
Gibbs S
,
Jackson M
,
Zare RN
,
Ehrt S
,
Ernst JD
et al.
. 2014.
LprG-mediated surface expression of lipoarabinomannan is essential for virulence of Mycobacterium tuberculosis.
.
PLoS Pathog. 10(9):e1004376.
Raju RM
,
Jedrychowski MP
,
Wei J-R
,
Pinkham JT
,
Park AS
,
O'Brien K
,
Rehren G
,
Schnappinger D
,
Gygi SP
,
Rubin EJ
. 2014.
Post-translational regulation via Clp protease is critical for survival of Mycobacterium tuberculosis.
.
PLoS Pathog. 10(3):e1003994.
2015
Sanders RW
,
van Gils MJ
,
Derking R
,
Sok D
,
Ketas TJ
,
Burger JA
,
Ozorowski G
,
Cupo A
,
Simonich C
,
Goo L
et al.
. 2015.
HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
.
Science. 349(6244):aac4223.
Zhao N
,
Sun M
,
Burns-Huang K
,
Jiang X
,
Ling Y
,
Darby C
,
Ehrt S
,
Liu G
,
Nathan C
. 2015.
Identification of Rv3852 as an Agrimophol-Binding Protein in Mycobacterium tuberculosis.
.
PLoS One. 10(5):e0126211.
Vaubourgeix J
,
Lin G
,
Dhar N
,
Chenouard N
,
Jiang X
,
Botella H
,
Lupoli T
,
Mariani O
,
Yang G
,
Ouerfelli O
et al.
. 2015.
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells.
.
Cell Host Microbe. 17(2):178-90.
Zhao N
,
Darby CM
,
Small J
,
Bachovchin DA
,
Jiang X
,
Burns-Huang KE
,
Botella H
,
Ehrt S
,
Boger DL
,
Anderson ED
et al.
. 2015.
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
.
ACS Chem Biol. 10(2):364-71.
2016
Gao M
,
Monian P
,
Pan Q
,
Zhang W
,
Xiang J
,
Jiang X
. 2016.
Ferroptosis is an autophagic cell death process.
.
Cell Res. 26(9):1021-32.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Van Voorhis WC
,
Adams JH
,
Adelfio R
,
Ahyong V
,
Akabas MH
,
Alano P
,
Alday A
,
Resto YAlemán
,
Alsibaee A
,
Alzualde A
et al.
. 2016.
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.
.
PLoS Pathog. 12(7):e1005763.
Li W
,
Obregón-Henao A
,
Wallach JB
,
E North J
,
Lee RE
,
Gonzalez-Juarrero M
,
Schnappinger D
,
Jackson M
. 2016.
Therapeutic Potential of the Mycobacterium tuberculosis Mycolic Acid Transporter, MmpL3.
.
Antimicrob Agents Chemother. 60(9):5198-207.
Korte J
,
Alber M
,
Trujillo CM
,
Syson K
,
Koliwer-Brandl H
,
Deenen R
,
Köhrer K
,
DeJesus MA
,
Hartman T
,
Jacobs WR
et al.
. 2016.
Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.
.
PLoS Pathog. 12(12):e1006043.
2017
Ruecker N
,
Jansen R
,
Trujillo C
,
Puckett S
,
Jayachandran P
,
Piroli GG
,
Frizzell N
,
Molina H
,
Rhee KY
,
Ehrt S
. 2017.
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.
.
Cell Chem Biol. 24(3):306-315.
Ruecker N
,
Jansen R
,
Trujillo C
,
Puckett S
,
Jayachandran P
,
Piroli GG
,
Frizzell N
,
Molina H
,
Rhee KY
,
Ehrt S
. 2017.
Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.
.
Cell Chem Biol. 24(3):306-315.
Janovitz T
,
Wong S
,
Young NS
,
Oliveira T
,
Falck-Pedersen E
. 2017.
Parvovirus B19 integration into human CD36+ erythroid progenitor cells.
.
Virology. 511:40-48.
Totaro KA
,
Barthelme D
,
Simpson PT
,
Jiang X
,
Lin G
,
Nathan C
,
Sauer RT
,
Sello JK
. 2017.
Rational Design of Selective and Bioactive Inhibitors of the Mycobacterium tuberculosis Proteasome.
.
ACS Infect Dis. 3(2):176-181.
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